Proteolysis targeting chimeras (PROTACs) technology has emerged as a novel therapeutic
paradigm in recent years. PROTACs are heterobifunctional molecules that degrade target …

Antibody-drug conjugates (ADCs) have emerged as a revolutionary therapeutic class,
combining the precise targeting ability of monoclonal antibodies with the potent cytotoxic …

Simple Summary Estrogens, belonging to a group of steroid compounds, play an important
role in both physiological and disease processes, mainly by interacting with estrogen …

Several chemotherapeutics against breast cancer are constrained by their adverse effects
and chemoresistance. The development of novel chemotherapeutics to target metastatic …

Approximately 70% of all breast cancer cases are estrogen receptor-alpha positive (ERα+)
and any ERα signaling pathways deregulation is critical for the progression of malignant …

Abstract The revolutionary Proteolysis Targeting Chimera (PROTACs) have the exciting
potential to reshape the pharmaceutical industry landscape by leveraging the ubiquitin …