Tryptophan synthase (TrpS) has emerged as a paragon of noncanonical amino acid (ncAA)
synthesis and is an ideal biocatalyst for synthetic and biological applications. TrpS catalyzes …

Azulene is a hydrocarbon isomer of naphthalene known for its unusual colour and
fluorescence properties. Through the harnessing of these properties, the literature has been …

Two-photon fluorescence microscopy has become an indispensable technique for cellular
imaging. Whereas most two-photon fluorescent probes rely on well-known fluorophores …

Many fluorescent proteins are currently available for biological spectroscopy and imaging
measurements, allowing a wide range of biochemical and biophysical processes and …

Azulenesulfonium salts may be readily prepared from the corresponding azulenes by an
SEAr reaction. These azulene sulfonium salts are bench‐stable species that may be …

We describe the synthesis and properties of azulene‐substituted 1, 1, 4, 4‐
tetracyanobutadienes (AzTCBDs) and heteroazulenyl TCBDs. TCBD derivatives were …

Allosteric information transfer in proteins has been linked to distinct vibrational energy
transfer (VET) pathways in a number of theoretical studies. Experimental evidence for such …

Tryptophan (Trp) and tryptophan derivatives are C2-arylated. AC–H activation process
allows the preparation of both protected and unprotected arylated-Trp amino acids, directly …

Fluorescent unnatural α-amino acids are widely used as probes in chemical biology and
medicinal chemistry. While a variety of structural classes have been developed, there is still …

Thiazoloindole α-amino acids have been synthesized in four steps from tryptophan using a
dual-catalytic thiolation reaction and a copper-mediated intramolecular N-arylation process …