The past decade has revealed the diversity and ubiquity of archaea in nature, with a growing
number of studies highlighting their importance in ecology, biotechnology and even human …

Candidate phyla radiation (CPR) bacteria and DPANN (an acronym of the names of the first
included phyla) archaea are massive radiations of organisms that are widely distributed …

Evolving concepts on Parkinson's disease (PD) pathology suggest that α-synuclein (aSYN)
promote dopaminergic neuron dysfunction and death through accumulating in the …

Archaea—a primary domain of life besides Bacteria—have for a long time been regarded as
peculiar organisms that play marginal roles in biogeochemical cycles. However, this picture …

All cell membranes are composed of glycerol phosphate phospholipids, and this
commonality argues for the presence of such phospholipids in the last common ancestor, or …

In this hypothesis article, we explore the origin of the eukaryotic nucleus. In doing so, we first
look afresh at the nature of this defining feature of the eukaryotic cell and its core functions …

Metagenomics has provided access to genomes of as yet uncultivated microorganisms in
natural environments, yet there are gaps in our knowledge—particularly for Archaea—that …

Biological features can be inferred, based on genomic data, for many microbial lineages that
remain uncultured. However, cultivation is important for characterizing an organism's …

In contrast to bacteria, all archaea possess cell walls lacking peptidoglycan and a number of
different cell envelope components have also been described. A paracrystalline protein …

Hard X-ray fluorescence microscopy is well-suited to in-situ investigations of trace metal
distributions within whole, unstained, biological tissue, with sub-parts-per-million detection …