Biology of cancer-testis antigens and their therapeutic implications in cancer
DS Nin, LW Deng - Cells, 2023 - mdpi.com
Tumour-specific antigens have been an area of interest in cancer therapy since their
discovery in the middle of the 20th century. In the era of immune-based cancer therapeutics …
discovery in the middle of the 20th century. In the era of immune-based cancer therapeutics …
Emerging contributions of cancer/testis antigens to neoplastic behaviors
Tumors of nearly every origin activate the expression of genes normally restricted to
gametogenic cells. These genes encode proteins termed cancer/testis (CT) antigens, since …
gametogenic cells. These genes encode proteins termed cancer/testis (CT) antigens, since …
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
The immunoproteasome plays a key role in generation of HLA peptides for T cell-mediated
immunity. Integrative genomic and proteomic analysis of non-small cell lung carcinoma …
immunity. Integrative genomic and proteomic analysis of non-small cell lung carcinoma …
A four‐gene‐based prognostic model predicts overall survival in patients with hepatocellular carcinoma
With the development of new advances in hepatocellular carcinoma (HCC) management
and noninvasive radiological techniques, high‐risk patient groups such as those with …
and noninvasive radiological techniques, high‐risk patient groups such as those with …
Fusobacterium nucleatum and its metabolite hydrogen sulfide alter gut microbiota composition and autophagy process and promote colorectal cancer progression
M Wang, Z Wang, DJ Lessing, M Guo… - Microbiology …, 2023 - Am Soc Microbiol
Fusobacterium nucleatum is a harmful bacterium that produces hydrogen sulfide by
metabolizing sulfur-containing amino acids, both of which have been shown to …
metabolizing sulfur-containing amino acids, both of which have been shown to …
[HTML][HTML] Cancer testis antigens and genomic instability: More than immunology
Cancer testis antigens or genes (CTA, CTG) are predominantly expressed in adult testes
while silenced in most or all somatic tissues with sporadic expression in many human …
while silenced in most or all somatic tissues with sporadic expression in many human …