Entamoeba histolytica is the etiological agent of amebiasis, which is an endemic parasitic
disease in develo** countries and is the cause of approximately 70,000 deaths annually …

The parasite Entamoeba histolytica causes amebic colitis and systemic amebiasis. Among
the known amebic factors contributing to pathogenesis are signaling pathways involving …

To understand the roles of phosphoinositides [PtdIns] in phagocytosis of parasitic
eukaryotes, we examined the interaction of phosphatidylinositol‐3‐phosphate [PtdIns (3) P] …

Entamoeba histolytica is a protozoan parasite and the causative agent of amoebiasis in
humans. This amoeba invades human tissues by taking advantage of its actin-rich …

Macropinocytosis is an evolutionarily conserved endocytic process that plays a vital role in
internalizing extracellular fluids and particles in cells. This non-selective endocytic pathway …

Exposure of Entamoeba histolytica to specific ligands induces cell polarization via the
activation of signalling pathways and cytoskeletal elements. The process leads to formation …

Entamoeba histolytica is a protozoan responsible for several pathologies in humans.
Trophozoites breach the intestinal site to enter the bloodstream and thus traverse to a …

Heterotrimeric G-protein signaling pathways are vital components of physiology, and many
are amenable to pharmacologic manipulation. Here, we identify functional heterotrimeric G …

Motility and phagocytosis are key processes that are involved in invasive amoebiasis
disease caused by intestinal parasite Entamoeba histolytica. Previous studies have reported …

Small GTPases are signalling molecules that regulate important cellular processes.
GTPases are deactivated by GTPase‐activating proteins (GAPs). While human GAPs have …