Large-scale association analyses identify host factors influencing human gut microbiome composition

A Kurilshikov, C Medina-Gomez, R Bacigalupe… - Nature …, 2021 - nature.com
To study the effect of host genetics on gut microbiome composition, the MiBioGen
consortium curated and analyzed genome-wide genotypes and 16S fecal microbiome data …

Obesity and eating behavior from the perspective of twin and genetic research

K Silventoinen, H Konttinen - Neuroscience & biobehavioral reviews, 2020 - Elsevier
Obesity has dramatically increased during the last decades and is currently one of the most
serious global health problems. We present a hypothesis that obesity is a neuro-behavioral …

The gut microbiota and depressive symptoms across ethnic groups

JA Bosch, M Nieuwdorp, AH Zwinderman… - Nature …, 2022 - nature.com
The gut microbiome is thought to play a role in depressive disorders, which makes it an
attractive target for interventions. Both the microbiome and depressive symptom levels vary …

The Netherlands twin register: longitudinal research based on twin and twin-family designs

L Ligthart, CEM van Beijsterveldt… - Twin Research and …, 2019 - cambridge.org
The Netherlands Twin Register (NTR) is a national register in which twins, multiples and
their parents, siblings, spouses and other family members participate. Here we describe the …

The interaction between microbiome and host central nervous system: the gut-brain axis as a potential new therapeutic target in the treatment of obesity and …

M Wijdeveld, M Nieuwdorp… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction The role of the intestinal microbiota in host cardiometabolic health and disease
has gained significant attention over recent decades. Previous studies have shown effects …

Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk

CT Finnicum, JJ Beck, CV Dolan, C Davis… - BMC microbiology, 2019 - Springer
Background The gut microbiota composition is known to be influenced by a myriad of factors
including the host genetic profile and a number of environmental influences. Here, we focus …

[HTML][HTML] The gut microbiome modulates associations between adherence to a Mediterranean-style diet, abdominal adiposity, and C-reactive protein in population …

A Jennings, T Kühn, NP Bondonno, S Waniek… - The American Journal of …, 2024 - Elsevier
Abstract Background Adherence to a Mediterranean-style dietary pattern is likely to have
variable effects on body composition, but the impact of gut microbiome on this relationship is …

An empirical Bayes approach to normalization and differential abundance testing for microbiome data

T Liu, H Zhao, T Wang - BMC bioinformatics, 2020 - Springer
Background Advances in DNA sequencing have offered researchers an unprecedented
opportunity to better study the variety of species living in and on the human body. However …

[HTML][HTML] Integrative and quantitative bioenergetics: Design of a study to assess the impact of the gut microbiome on host energy balance

KD Corbin, R Krajmalnik-Brown, EA Carnero… - Contemporary clinical …, 2020 - Elsevier
The literature is replete with clinical studies that characterize the structure, diversity, and
function of the gut microbiome and correlate the results to different disease states, including …

Chimerism in health and potential implications on behavior: A systematic review

BN Johnson, EA Ehli, GE Davies… - American Journal of …, 2020 - Wiley Online Library
In this review, we focus on the phenomenon of chimerism and especially microchimerism as
one of the currently underexplored explanations for differences in health and behavior …