Neuroinflammation is a key component of neurological disorders and is an important
therapeutic target; however, immunotherapies have been largely unsuccessful. In cases …

Axonal loss in multiple sclerosis (MS) is a key component of disease progression and
permanent neurologic disability. MS is a heterogeneous demyelinating and …

Background Observational studies have suggested an association between multiple
sclerosis (MS) and cortical structure, but the results have been inconsistent. Objective We …

Pathological data showed focal inflammation and regions of diffuse neuronal loss in the
cortex of people with multiple sclerosis (MS). In this work, we applied a novel model (“soma …

This study examined the roles of microglia and monocytes in myelin destruction in patients
with early multiple sclerosis (MS). Twenty-two cases were studied; the clinical duration was< …

This review delves into neuroimmunology, focusing on its relevance to multiple sclerosis
(MS) and potential treatment advancements. Neuroimmunology explores the intricate …

Background Cognitive dysfunction is common among patients with multiple sclerosis (MS);
however, the determinants of cognitive dysfunction are still unknown. This study aimed to …

The study was designed to examine microglia morphology in early and late forms of multiple
sclerosis (MS). Archival paraffin embedded tissue samples from 25 cases were examined …

Background Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is
an uncommon neurological disease affecting the central nervous system (CNS). Numerous …

Objective: To assess the reliability of phase-sensitive inversion recovery (PSIR) magnetic
resonance imaging (MRI) and its accuracy for determining the topography of demyelinating …