Hybrid modeling for biopharmaceutical processes: advantages, opportunities, and implementation

H Narayanan, M von Stosch, F Feidl… - Frontiers in Chemical …, 2023‏ - frontiersin.org
Process models are mathematical formulations (essentially a set of equations) that try to
represent the real system/process in a digital or virtual form. These are derived either based …

[HTML][HTML] Navigating the DevOps landscape

X Zhang, P Zhao, J Jaskolka - Journal of Systems and Software, 2025‏ - Elsevier
Context: DevOps, with its increasing prevalence in both industry and academia, has evolved
into various DevOps variants (namely XOps) to address emerging technological and …

Automated High-Throughput Partition Coefficient Determination with Image Analysis for Rapid Reaction Workup Process Development and Modeling

S Duffield, L Da Vià, AC Bellman… - … Process Research & …, 2021‏ - ACS Publications
With this work, we explore the application of a novel image analysis algorithm in
combination with a high-throughput automated workflow to extract partition coefficient …

Digital twin implementation for manufacturing of adjuvants

P Phalak, E Tomba, P Jehoulet, A Kapitan-Gnimdu… - Processes, 2023‏ - mdpi.com
Pharmaceutical manufacturing processes are moving towards automation and real-time
process monitoring with the help of process analytical technologies (PATs) and predictive …

Towards Long-Term Scientific Model Sustainment at Sandia National Laboratories

C Gilbertson, R Milewicz, E Berquist… - Proceedings of the 39th …, 2024‏ - dl.acm.org
Scientific modeling and simulation software is ubiquitous at Sandia National Laboratories
and is integral to providing empirical justification to critical mission decisions. Models are …