The role of serotonin in depression—A historical roundup and future directions

S Bremshey, J Groß, K Renken… - Journal of …, 2024 - Wiley Online Library
Depression is one of the most common psychiatric disorders worldwide, affecting
approximately 280 million people, with probably much higher unrecorded cases …

Extracting value from total-body PET/CT image data-the emerging role of artificial intelligence

LK Shiyam Sundar, S Gutschmayer, M Maenle, T Beyer - Cancer Imaging, 2024 - Springer
Abstract The evolution of Positron Emission Tomography (PET), culminating in the Total-
Body PET (TB-PET) system, represents a paradigm shift in medical imaging. This paper …

Map** neurotransmitter systems to the structural and functional organization of the human neocortex

JY Hansen, G Shafiei, RD Markello, K Smart… - Nature …, 2022 - nature.com
Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape …

Neuromaps: structural and functional interpretation of brain maps

RD Markello, JY Hansen, ZQ Liu, V Bazinet, G Shafiei… - Nature …, 2022 - nature.com
Imaging technologies are increasingly used to generate high-resolution reference maps of
brain structure and function. Comparing experimentally generated maps to these reference …

Local molecular and global connectomic contributions to cross-disorder cortical abnormalities

JY Hansen, G Shafiei, JW Vogel, K Smart… - Nature …, 2022 - nature.com
Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …

A high-resolution in vivo atlas of the human brain's serotonin system

V Beliveau, M Ganz, L Feng, B Ozenne… - Journal of …, 2017 - jneurosci.org
The serotonin (5-hydroxytryptamine, 5-HT) system modulates many important brain
functions and is critically involved in many neuropsychiatric disorders. Here, we present a …
AI Luppi, JY Hansen, R Adapa, RL Carhart-Harris… - Science …, 2023 - science.org
To understand how pharmacological interventions can exert their powerful effects on brain
function, we need to understand how they engage the brain's rich neurotransmitter …

Psilocybin-induced decrease in amygdala reactivity correlates with enhanced positive mood in healthy volunteers

R Kraehenmann, KH Preller, M Scheidegger… - Biological …, 2015 - Elsevier
Background The amygdala is a key structure in serotonergic emotion-processing circuits. In
healthy volunteers, acute administration of the serotonin 1A/2A/2C receptor agonist …

Activation of serotonin 2A receptors underlies the psilocybin-induced effects on α oscillations, N170 visual-evoked potentials, and visual hallucinations

M Kometer, A Schmidt, L Jäncke… - Journal of …, 2013 - jneurosci.org
Visual illusions and hallucinations are hallmarks of serotonergic hallucinogen-induced
altered states of consciousness. Although the serotonergic hallucinogen psilocybin activates …