Deuterium‐and tritium‐labelled compounds: applications in the life sciences

J Atzrodt, V Derdau, WJ Kerr… - Angewandte chemie …, 2018 - Wiley Online Library
Hydrogen isotopes are unique tools for identifying and understanding biological and
chemical processes. Hydrogen isotope labelling allows for the traceless and direct …

Protein analysis by shotgun/bottom-up proteomics

Y Zhang, BR Fonslow, B Shan, MC Baek… - Chemical …, 2013 - ACS Publications
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …

Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses

GC McAlister, EL Huttlin, W Haas, L Ting… - Analytical …, 2012 - ACS Publications
Quantitative mass spectrometry methods offer near-comprehensive proteome coverage;
however, these methods still suffer with regards to sample throughput. Multiplex quantitation …

Quantitative proteomics using isobaric labeling: a practical guide

X Chen, Y Sun, T Zhang, L Shu… - Genomics …, 2021 - academic.oup.com
In the past decade, relative proteomic quantification using isobaric labeling technology has
developed into a key tool for comparing the expression of proteins in biological samples …

Quantitative mass spectrometry in proteomics: a critical review

M Bantscheff, M Schirle, G Sweetman, J Rick… - Analytical and …, 2007 - Springer
The quantification of differences between two or more physiological states of a biological
system is among the most important but also most challenging technical tasks in proteomics …

Stable isotope labelling methods in mass spectrometry-based quantitative proteomics

O Chahrour, D Cobice, J Malone - Journal of pharmaceutical and …, 2015 - Elsevier
Mass-spectrometry based proteomics has evolved as a promising technology over the last
decade and is undergoing a dramatic development in a number of different areas, such as; …

Mass spectrometry–based proteomics turns quantitative

SE Ong, M Mann - Nature chemical biology, 2005 - nature.com
The field of proteomics is built on technologies to analyze large numbers of proteins—ideally
the entire proteome—in the same experiment. Mass spectrometry (MS) has been …

Current two‐dimensional electrophoresis technology for proteomics

A Görg, W Weiss, MJ Dunn - Proteomics, 2004 - Wiley Online Library
Abstract Two‐dimensional gel electrophoresis (2‐DE) with immobilized pH gradients (IPGs)
combined with protein identification by mass spectrometry (MS) is currently the workhorse …

Proteomics: a pragmatic perspective

P Mallick, B Kuster - Nature biotechnology, 2010 - nature.com
The evolution of mass spectrometry–based proteomic technologies has advanced our
understanding of the complex and dynamic nature of proteomes while concurrently …

[KİTAP][B] Peptides: chemistry and biology

N Sewald, HD Jakubke - 2015 - books.google.com
Der" Sewald/Jakubke" ist und bleibt das einzige moderne, auf dem neuesten
wissenschaftlichen Stand gehaltene fortgeschrittene Lehrbuch der Peptid-Biochemie! Auch …