Background: Associations between paraoxonase 1 (PON1) gene polymorphisms and heart
diseases (HD) risk remain inconsistent. In order to obtain address this issue we performed a …

The wide acceptance of the oxidation theory of atherogenesis has prompted attention to
antioxidant mechanisms, particularly the prevention of lipid oxidation by high-density …

OBJECTIVE: The human paraoxonase (PON) is calcium dependent HDL associated ester
hydrolase which has attracted considerable attention as a candidate gene for coronary heart …

Decreased paraoxonase-1 (PON1) activity has been associated with rheumatoid arthritis.
There are two polymorphisms in serum PON1; one differs in the amino acid at position 192 …

Results: Immunohistochemical analysis showed that PON1 expression was lower in
atherosclerotic arteries than in normal arteries. PON1 Q192R (rs662) had a significant effect …

Worldwide prevalence of diabetes mellitus motivates a number of association studies to be
conducted throughout the world. Eleven polymorphisms from nine candidate genes in …

Coronary artery disease (CAD) has emerged as a major cause of morbidity and mortality
worldwide. Recent findings on the role of genetic factors in the aetiopathology of CAD have …

Background: The present case–control study evaluated the association of PON1 gene
polymorphisms and enzyme activity in the western Indian population. Materials & methods …

Diabetes mellitus is a multifactorial metabolic disease, caused by the complete or relative
absence of insulin hormone, which results in the deterioration of carbohydrate, protein, and …

PURPOSE: To investigate the potential interaction between folate intake and the
paraoxonase 1 (PON1) Q192R polymorphism with the risk of incident coronary heart …