[HTML][HTML] Effects of physical exercise on cognitive functioning and wellbeing: biological and psychological benefits

L Mandolesi, A Polverino, S Montuori, F Foti… - Frontiers in …, 2018 - frontiersin.org
Much evidence shows that physical exercise (PE) is a strong gene modulator that induces
structural and functional changes in the brain, determining enormous benefit on both …

Neurobiology of BDNF in fear memory, sensitivity to stress, and stress-related disorders

M Notaras, M van den Buuse - Molecular psychiatry, 2020 - nature.com
Brain-derived neurotrophic factor (BDNF) is widely accepted for its involvement in resilience
and antidepressant drug action, is a common genetic locus of risk for mental illnesses, and …

Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs

A Tomar, M Gomez-Velazquez, R Gerlini… - Nature, 2024 - nature.com
Spermatozoa harbour a complex and environment-sensitive pool of small non-coding RNAs
(sncRNAs), which influences offspring development and adult phenotypes,,,,,–. Whether …

[HTML][HTML] The role of the epididymis and the contribution of epididymosomes to mammalian reproduction

ER James, DT Carrell, KI Aston, TG Jenkins… - International journal of …, 2020 - mdpi.com
It is well-established that testicular spermatozoa are immature and acquire motility and
fertilization capabilities during transit throughout the epididymis. The epididymis is a duct …

Adolescence and the next generation

GC Patton, CA Olsson, V Skirbekk, R Saffery… - Nature, 2018 - nature.com
Adolescent growth and social development shape the early development of offspring from
preconception through to the post-partum period through distinct processes in males and …

How does epigenetics influence the course of evolution?

A Ashe, V Colot, BP Oldroyd - … transactions of the …, 2021 - royalsocietypublishing.org
Epigenetics is the study of changes in gene activity that can be transmitted through cell
divisions but cannot be explained by changes in the DNA sequence. Epigenetic …

Physical exercise as an epigenetic modulator of brain plasticity and cognition

J Fernandes, RM Arida, F Gomez-Pinilla - Neuroscience & Biobehavioral …, 2017 - Elsevier
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

Epigenetic inheritance: concepts, mechanisms and perspectives

I Lacal, R Ventura - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

Transfer RNA-derived fragments and tRNA halves: biogenesis, biological functions and their roles in diseases

Y Shen, X Yu, L Zhu, T Li, Z Yan, J Guo - Journal of Molecular Medicine, 2018 - Springer
The number of studies on non-coding RNAs has increased substantially in recent years
owing to their importance in gene regulation. However, the biological functions of small …

[HTML][HTML] Paternal phthalate exposure-elicited offspring metabolic disorders are associated with altered sperm small RNAs in mice

J Liu, J Shi, R Hernandez, X Li, P Konchadi… - Environment …, 2023 - Elsevier
Exposure to ubiquitous plastic-associated endocrine disrupting chemicals (EDCs) is
associated with the increased risk of many chronic diseases. For example, phthalate …