Therapeutic cancer vaccines

M Saxena, SH van der Burg, CJM Melief… - Nature Reviews …, 2021 - nature.com
Therapeutic cancer vaccines have undergone a resurgence in the past decade. A better
understanding of the breadth of tumour-associated antigens, the native immune response …

Targeted drug delivery strategies for precision medicines

MT Manzari, Y Shamay, H Kiguchi, N Rosen… - Nature Reviews …, 2021 - nature.com
Progress in the field of precision medicine has changed the landscape of cancer therapy.
Precision medicine is propelled by technologies that enable molecular profiling, genomic …

Designing spatial and temporal control of vaccine responses

GA Roth, VCTM Picece, BS Ou, W Luo… - Nature Reviews …, 2022 - nature.com
Vaccines are the key technology to combat existing and emerging infectious diseases.
However, increasing the potency, quality and durability of the vaccine response remains a …

Thermal immuno-nanomedicine in cancer

Z Yang, D Gao, J Zhao, G Yang, M Guo… - Nature Reviews …, 2023 - nature.com
Immunotherapy has revolutionized the treatment of patients with cancer. However,
promoting antitumour immunity in patients with tumours that are resistant to these therapies …

A general strategy towards personalized nanovaccines based on fluoropolymers for post-surgical cancer immunotherapy

J Xu, J Lv, Q Zhuang, Z Yang, Z Cao, L Xu, P Pei… - Nature …, 2020 - nature.com
Cancer metastases and recurrence after surgical resection remain an important cause of
treatment failure. Here we demonstrate a general strategy to fabricate personalized …

A DNA nanodevice-based vaccine for cancer immunotherapy

S Liu, Q Jiang, X Zhao, R Zhao, Y Wang, Y Wang… - Nature Materials, 2021 - nature.com
A major challenge in cancer vaccine therapy is the efficient delivery of antigens and
adjuvants to stimulate a controlled yet robust tumour-specific T-cell response. Here, we …

Materials engineering strategies for cancer vaccine adjuvant development

X Zhang, B Yang, Q Ni, X Chen - Chemical Society Reviews, 2023 - pubs.rsc.org
Cancer vaccines have emerged as a powerful new tool for cancer immunotherapy.
Adjuvants are vaccine ingredients that enhance the strength, velocity, and duration of the …

Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Delivery technologies for cancer immunotherapy

RS Riley, CH June, R Langer, MJ Mitchell - Nature reviews Drug …, 2019 - nature.com
Immunotherapy has become a powerful clinical strategy for treating cancer. The number of
immunotherapy drug approvals has been increasing, with numerous treatments in clinical …

Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches

TB Emran, A Shahriar, AR Mahmud, T Rahman… - Frontiers in …, 2022 - frontiersin.org
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …