The role and activity of SWI/SNF chromatin remodelers
T Bieluszewski, S Prakash, T Roulé… - Annual Review of Plant …, 2023 - annualreviews.org
SWITCH deficient SUCROSE NONFERMENTING (SWI/SNF) class chromatin remodeling
complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of …
complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of …
An RNA-centric view of transcription and genome organization
Foundational models of transcriptional regulation involve the assembly of protein complexes
at DNA elements associated with specific genes. These assemblies, which can include …
at DNA elements associated with specific genes. These assemblies, which can include …
C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
Summary Cys2-His2 zinc-finger proteins (C2H2-ZNFs) constitute the largest class of DNA-
binding transcription factors (TFs) yet remain largely uncharacterized. Although certain …
binding transcription factors (TFs) yet remain largely uncharacterized. Although certain …
The role of SAF-A/hnRNP U in regulating chromatin structure
Scaffold attachment factor A (SAF-A) or hnRNP U is a nuclear RNA-binding protein with a
well-documented role in processing newly transcribed RNA. Recent studies also indicate …
well-documented role in processing newly transcribed RNA. Recent studies also indicate …
TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV
Abstract The Human Silencing Hub (HUSH) complex constituted of TASOR, MPP8 and
Periphilin recruits the histone methyl-transferase SETDB1 to spread H3K9me3 repressive …
Periphilin recruits the histone methyl-transferase SETDB1 to spread H3K9me3 repressive …
Nuclear RNA: a transcription-dependent regulator of chromatin structure
J Stocks, N Gilbert - Biochemical Society Transactions, 2024 - portlandpress.com
Although the majority of RNAs are retained in the nucleus, their significance is often
overlooked. However, it is now becoming clear that nuclear RNA forms a dynamic structure …
overlooked. However, it is now becoming clear that nuclear RNA forms a dynamic structure …
Enhancer RNAs in transcriptional regulation: recent insights
Q Chen, Y Zeng, J Kang, M Hu, N Li, K Sun… - Frontiers in cell and …, 2023 - frontiersin.org
Enhancers are a class of cis-regulatory elements in the genome that instruct the
spatiotemporal transcriptional program. Last decade has witnessed an exploration of non …
spatiotemporal transcriptional program. Last decade has witnessed an exploration of non …
PRC2 direct transfer from G-quadruplex RNA to dsDNA has implications for RNA-binding chromatin modifiers
WO Hemphill, R Fenske… - Proceedings of the …, 2023 - National Acad Sciences
The chromatin-modifying enzyme, Polycomb Repressive Complex 2 (PRC2), deposits the
H3K27me3 epigenetic mark to negatively regulate expression at numerous target genes …
H3K27me3 epigenetic mark to negatively regulate expression at numerous target genes …
The DNA binding high mobility group box protein family functionally binds RNA
DJ Hamilton, AE Hein, DS Wuttke… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Nucleic acid binding proteins regulate transcription, splicing, RNA stability, RNA localization,
and translation, together tailoring gene expression in response to stimuli. Upon discovery …
and translation, together tailoring gene expression in response to stimuli. Upon discovery …
Increased transcriptional elongation and RNA stability of GPCR ligand binding genes unveiled via RNA polymerase II degradation
L Bao, J Zhu, T Shi, Y Jiang, B Li… - Nucleic Acids …, 2024 - academic.oup.com
RNA polymerase II drives mRNA gene expression, yet our understanding of Pol II
degradation is limited. Using auxin-inducible degron, we degraded Pol II's RPB1 subunit …
degradation is limited. Using auxin-inducible degron, we degraded Pol II's RPB1 subunit …