Fluorescent probe strategy for live cell distinction

X Liu, YT Chang - Chemical Society Reviews, 2022 - pubs.rsc.org
Live cell discrimination is the first and essential step to understand complex biosystems.
Conventional cell discrimination involving various antibodies relies on selective surface …

Chronological development of functional fluorophores for bio-imaging

S Munan, YT Chang, A Samanta - Chemical Communications, 2024 - pubs.rsc.org
Functional fluorophores represent an emerging research field, distinguished by their diverse
applications, especially in sensing and cellular imaging. After the discovery of quinine …

The two weapons against bacterial biofilms: Detection and treatment

A Cruz, M Condinho, B Carvalho, CM Arraiano… - Antibiotics, 2021 - mdpi.com
Bacterial biofilms are defined as complex aggregates of bacteria that grow attached to
surfaces or are associated with interfaces. Bacteria within biofilms are embedded in a self …

Clearing an ESKAPE pathogen in a model organism; a polypyridyl ruthenium (II) complex theranostic that treats a resistant Acinetobacter baumannii infection in …

K Smitten, HM Southam, S Fairbanks… - … A European Journal, 2023 - Wiley Online Library
In previous studies we have described the therapeutic action of luminescent dinuclear
ruthenium (II) complexes based on the tetrapyridylphenazine, tpphz, bridging ligand on …

High‐Sucrose Diet Accelerates Arthritis Progression in a Collagen‐Induced Rheumatoid Arthritis Model

Y Min, Y Heo, F Feng, D Kim, M Kim… - Molecular Nutrition & …, 2023 - Wiley Online Library
Scope High dietary sugar and sweeteners are suspected to cause the development of
rheumatoid arthritis (RA) symptoms through the induction of proinflammatory cytokine …

Yersinia enterocolitica-Derived Outer Membrane Vesicles Inhibit Initial Stage of Biofilm Formation

G Ma, Y Ding, Q Wu, J Zhang, M Liu, Z Wang, Z Wang… - Microorganisms, 2022 - mdpi.com
Yersinia enterocolitica (Y. enterocolitica) is an important food-borne and zoonotic pathogen.
It can form biofilm on the surface of food, increasing the risk to food safety. Generally, outer …

Imaging and Therapy of Tumors Based on Neutrophil Extracellular Traps

Y Hao, D Liu, K Wang, Q Liu, H Chen, S Ji… - Small …, 2024 - Wiley Online Library
Neutrophil extracellular traps (NETs) formed by neutrophils are netlike scaffolds that mainly
contain DNA and a variety of granule proteins. Many stimuli can lead to the NET formation …

Targeted anti-biofilm therapy: Dissecting targets in the biofilm life cycle

F Bu, M Liu, Z **e, X Chen, G Li, X Wang - Pharmaceuticals, 2022 - mdpi.com
Biofilm is a crucial virulence factor for microorganisms that causes chronic infection. After
biofilm formation, the bacteria present improve drug tolerance and multifactorial defense …

Discovery of Live Cell Selective Fluorescent Probes and Elucidation of Their Mechanisms: Case Study of B Cell Selective Probe CDgB

HY Kwon, YT Chang, NY Kang - Flow Cytometry Protocols, 2024 - Springer
The development of small-molecule fluorescent probes for specific immune cell identification
offers an economical alternative to expensive antibodies. Moreover, it enables the …

Validation of CDr15 as a new dye for detecting neutrophil extracellular trap

SJ Kim, J Kim, B Kim, WW Lee, X Liu, YT Chang… - Biochemical and …, 2020 - Elsevier
Neutrophil extracellular trap (NET) is one of the first-line defenses against microbes. Under
certain circumstances, however, it also plays an aggravating factor in diverse inflammation …