Alkaloids for cancer prevention and therapy: Current progress and future perspectives
A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …
Papaverine: a miraculous alkaloid from opium and its multimedicinal application
The pharmacological actions of benzylisoquinoline alkaloids are quite substantial, and have
recently attracted much attention. One of the principle benzylisoquinoline alkaloids has been …
recently attracted much attention. One of the principle benzylisoquinoline alkaloids has been …
Novel papaverine metal complexes with potential anticancer activities
Cancer is one of the leading causes of death worldwide. Although several potential
therapeutic agents have been developed to efficiently treat cancer, some side effects can …
therapeutic agents have been developed to efficiently treat cancer, some side effects can …
DARK classics in chemical neuroscience: opium, a historical perspective
CC Presley, CW Lindsley - ACS Chemical Neuroscience, 2018 - ACS Publications
Opium is the latex from the opium poppy Papaver somniferum L., which humankind has
utilized since ancient Mesopotamia all the way to modern times. Opium used to be …
utilized since ancient Mesopotamia all the way to modern times. Opium used to be …
Enhanced cytotoxic activity of curcumin on cancer cell lines by incorporating into gold/chitosan nanogels
N Amanlou, M Parsa, K Rostamizadeh… - Materials chemistry and …, 2019 - Elsevier
The present research reports the successful synthesis of curcumin loaded core–shell
nanostructures composed of gold nanoparticles and chitosan. Gold nanoparticles were …
nanostructures composed of gold nanoparticles and chitosan. Gold nanoparticles were …
Fabrication of sustained release curcumin-loaded solid lipid nanoparticles (cur-SLNs) as a potential drug delivery system for the treatment of lung cancer: Optimization …
The goal of current research was to develop a new form of effective drug, curcumin-loaded
solid lipid nanoparticles (Cur-SLNs) and test its efficacy in the treatment of lung cancer …
solid lipid nanoparticles (Cur-SLNs) and test its efficacy in the treatment of lung cancer …
Anticancer effects of a non-narcotic opium alkaloid medicine, papaverine, in human glioblastoma cells
M Inada, M Shindo, K Kobayashi, A Sato… - PLoS …, 2019 - journals.plos.org
The interaction between high-mobility group box 1 protein (HMGB1) and receptor for
advanced glycation end products (RAGE) is important for tumor cell growth. We investigated …
advanced glycation end products (RAGE) is important for tumor cell growth. We investigated …
The biological relevance of papaverine in cancer cells
Papaverine (PPV), a benzylisoquinoline alkaloid, extracted from the Papaverine somniferum
plant, is currently in clinical use as a vasodilator. Research has shown that PPV inhibits …
plant, is currently in clinical use as a vasodilator. Research has shown that PPV inhibits …
Review on physicochemical, medicinal and nutraceutical properties of poppy seeds: a potential functional food ingredient
The poppy seed plant (Papaver somniferum L.) is well known for its health benefits. It
contains plenty of nutrients including proteins, oil content, dietary fiber, antioxidants …
contains plenty of nutrients including proteins, oil content, dietary fiber, antioxidants …
Update of the scientific opinion on opium alkaloids in poppy seeds
EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2018 - Wiley Online Library
Poppy seeds are obtained from the opium poppy (Papaver somniferum L.). They are used
as food and to produce edible oil. The opium poppy plant contains narcotic alkaloids such …
as food and to produce edible oil. The opium poppy plant contains narcotic alkaloids such …