Cancer spheroids and organoids as novel tools for research and therapy: state of the art and challenges to guide precision medicine

S El Harane, B Zidi, N El Harane, KH Krause, T Matthes… - Cells, 2023 - mdpi.com
Spheroids and organoids are important novel players in medical and life science research.
They are gradually replacing two-dimensional (2D) cell cultures. Indeed, three-dimensional …

[HTML][HTML] Towards resource-efficient and cost-efficient cultured meat

S Hubalek, MJ Post, P Moutsatsou - Current Opinion in Food Science, 2022 - Elsevier
Cultured meat is a bearer of hope for sustainable meat production, aiming at ensuring global
food security while preserving environmental resources. Being a nascent industry, there are …

Tunable fluorescent carbon dots from biowaste as fluorescence ink and imaging human normal and cancer cells

R Atchudan, SC Kishore, P Gangadaran… - Environmental …, 2022 - Elsevier
Growing global biowaste and its environmental issues challenge the need for converting
biowastes into a beneficial product. Among the biowaste, here kiwi fruit (Actinidia Deliciosa) …

3D bioprinted multilayered cerebrovascular conduits to study cancer extravasation mechanism related with vascular geometry

W Park, JS Lee, G Gao, BS Kim, DW Cho - Nature communications, 2023 - nature.com
Cerebral vessels are composed of highly complex structures that facilitate blood perfusion
necessary for meeting the high energy demands of the brain. Their geometrical complexities …

[HTML][HTML] 3D printing of bio-instructive materials: Toward directing the cell

PS Zieliński, PKR Gudeti, T Rikmanspoel… - Bioactive Materials, 2023 - Elsevier
Fabrication of functional scaffolds for tissue engineering and regenerative medicine
applications requires material systems with precise control over cellular performance. 3D …

Co-culture approaches for cultivated meat production

S David, A Tsukerman, D Safina… - Nature Reviews …, 2023 - nature.com
The need and demand for sustainable, nutritious and animal-welfare-conscious meat
substitutes has spurred research into cultivated meat production. Meat mainly contains …

Cell culture‐derived extracellular vesicles: Considerations for reporting cell culturing parameters

F Shekari, FJ Alibhai, H Baharvand… - Journal of …, 2023 - Wiley Online Library
Cell culture‐conditioned medium (CCM) is a valuable source of extracellular vesicles (EVs)
for basic scientific, therapeutic and diagnostic applications. Cell culturing parameters affect …

[HTML][HTML] Experimental human placental models for studying uptake, transport and toxicity of micro-and nanoplastics

HM Dusza, J van Boxel, MBM van Duursen… - Science of the Total …, 2023 - Elsevier
Micro-and nanoplastics (MNPs) are ubiquitous in the environment and have recently been
found in human lungs, blood and placenta. However, data on the possible effects of MNPs …

Exploring tumor–immune interactions in co-culture models of T cells and tumor organoids derived from patients

SR Jeong, M Kang - International Journal of Molecular Sciences, 2023 - mdpi.com
The use of patient-derived tumor tissues and cells has led to significant advances in
personalized cancer therapy and precision medicine. The advent of genomic sequencing …

[HTML][HTML] Bone regeneration and oxidative stress: an updated overview

AE Bădilă, DM Rădulescu, A Ilie, AG Niculescu… - Antioxidants, 2022 - mdpi.com
Bone tissue engineering is a complex domain that requires further investigation and benefits
from data obtained over past decades. The models are increasing in complexity as they …