The role of inflammation and genetics in periodontal disease

BG Loos, TE Van Dyke - Periodontology 2000, 2020‏ - Wiley Online Library
Periodontitis is a complex disease:(a) various causative factors play a role simultaneously
and interact with each other; and (b) the disease is episodic in nature, and bursts of disease …

Role of inflammasomes in the pathogenesis of periodontal disease and therapeutics

JT Marchesan, MS Girnary, K Moss… - Periodontology …, 2020‏ - Wiley Online Library
Inflammasomes are a group of multimolecular intracellular complexes assembled around
several innate immune proteins. Recognition of a diverse range of microbial, stress and …

Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier

LM Silva, AD Doyle, T Greenwell-Wild, N Dutzan… - Science, 2021‏ - science.org
INTRODUCTION Mucosal barrier sites are continuously exposed to diverse environmental
stimuli, and the fine-tuning of mucosal tissue–specific immune responses is key to …

Periodontal disease, regular dental care use, and incident ischemic stroke

S Sen, LD Giamberardino, K Moss, T Morelli… - Stroke, 2018‏ - ahajournals.org
Background and Purpose—Periodontal disease is independently associated with
cardiovascular disease. Identification of periodontal disease as a risk factor for incident …

Clinical application of the new classification of periodontal diseases: Ground rules, clarifications and “gray zones”

KS Kornman, PN Papapanou - Journal of periodontology, 2020‏ - Wiley Online Library
Background Successful dissemination of the new classification of periodontitis is facilitated
by emphasis on the basic ground rules, clarification of ambiguities, and identification of “gray …

Dental caries, race and incident ischemic stroke, coronary heart disease, and death

S Sen, L Logue, M Logue, EAL Otersen, E Mason… - Stroke, 2024‏ - ahajournals.org
BACKGROUND: Dental caries is a highly prevalent disease worldwide. In the United States,
untreated dental caries is present in> 1 in 5 adults. The objective of this study was to …

Interdental cleaning is associated with decreased oral disease prevalence

JT Marchesan, T Morelli, K Moss… - Journal of dental …, 2018‏ - journals.sagepub.com
The purpose of this study was to evaluate the associations between interdental cleaning
behavior and the prevalence of caries and periodontal disease and numbers of missing …

Periodontal profile class is associated with prevalent diabetes, coronary heart disease, stroke, and systemic markers of C‐reactive protein and interleukin‐6

JD Beck, KL Moss, T Morelli… - Journal of …, 2018‏ - Wiley Online Library
Background This paper focuses on the Periodontal Profile Class (PPC) System that may be
more informative and representative of periodontitis phenotypes than current case …

Periodontal disease and incident dementia: the Atherosclerosis Risk in Communities Study (ARIC)

RT Demmer, FL Norby, K Lakshminarayan, KA Walker… - Neurology, 2020‏ - neurology.org
Objective To test the hypothesis that periodontal disease would be associated with
increased risk for dementia and mild cognitive impairment (MCI) by assessing dementia/MCI …

Flossing is associated with improved oral health in older adults

JT Marchesan, KM Byrd, K Moss… - Journal of dental …, 2020‏ - journals.sagepub.com
The effect of preventive oral habits is largely unexplored in older individuals. The purpose of
this study was to evaluate the associations between home use of flossing and prevalence of …