Abstract pH is tightly maintained at cellular, tissue, and systemic levels, and altered pH–
particularly in the acidic range–is associated with infection, injury, solid tumors, and …

As the most prevalent transition metals, iron (Fe), zinc (Zn), and copper (Cu) hold
significance across a wide variety of essential biological functions in living systems, and …

The tumor microenvironment (TME) demonstrates distinct hallmarks, including acidosis,
hypoxia, reactive oxygen species (ROS) generation, and altered ion fluxes, which are crucial …

Ratiometric fluorescence nanosensors provide quantitative biological information. However,
spectral shift and distortion of ratiometric nanosensors in biological media often compromise …

Photobase generators (PBGs) are compounds that utilize light-sensitive chemical-protecting
groups to offer spatiotemporal control of releasing organic bases upon targeted light …

Prior research establishing that bone interacts in coordination with the bone marrow
microenvironment (BMME) to regulate hematopoietic homeostasis was largely based on …

Calcium, an indispensable element in bone tissues, plays a crucial role in various cellular
processes involved in cancer progression. Its ubiquitous yet spatially distinct distribution in …

This work reports the development of a biomimetic membrane-wrapped nanoparticle
(MWNP) platform for targeted chemotherapy of acute myeloid leukemia (AML). Doxorubicin …

Abstract Purpose of Review This review summarizes the recently published scientific
evidence regarding the role of efferocytosis in bone dynamics and skeletal health. Recent …

Heterotopic ossification (HO) is a condition triggered by an injury leading to the formation of
mature lamellar bone in extraskeletal soft tissues. Despite being a frequent complication of …