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[HTML][HTML] Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses
Viruses that replicate in the human respiratory mucosa without infecting systemically,
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
Over the past several decades, messenger RNA (mRNA) vaccines have progressed from a
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
scepticism-inducing idea to clinical reality. In 2020, the COVID-19 pandemic catalysed the …
Nirsevimab for prevention of hospitalizations due to RSV in infants
Background The safety of the monoclonal antibody nirsevimab and the effect of nirsevimab
on hospitalizations for respiratory syncytial virus (RSV)–associated lower respiratory tract …
on hospitalizations for respiratory syncytial virus (RSV)–associated lower respiratory tract …
Nirsevimab and hospitalization for RSV bronchiolitis
Background Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis, resulting
in 3 million hospitalizations each year worldwide. Nirsevimab is a monoclonal antibody …
in 3 million hospitalizations each year worldwide. Nirsevimab is a monoclonal antibody …
Nirsevimab for prevention of RSV in healthy late-preterm and term infants
Background Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract
infection and hospitalization in infants. Nirsevimab is a monoclonal antibody to the RSV …
infection and hospitalization in infants. Nirsevimab is a monoclonal antibody to the RSV …
Mucosal vaccines—fortifying the frontiers
Mucosal vaccines offer the potential to trigger robust protective immune responses at the
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …
predominant sites of pathogen infection. In principle, the induction of adaptive immunity at …
RSV prevention in all infants: which is the most preferable strategy?
Respiratory syncytial virus (RSV) causes a spectrum of respiratory illnesses in infants and
young children that may lead to hospitalizations and a substantial number of outpatient …
young children that may lead to hospitalizations and a substantial number of outpatient …
Pediatric Infectious Disease Group (GPIP) position paper on the immune debt of the COVID-19 pandemic in childhood, how can we fill the immunity gap?
Since the beginning of the COVID-19 pandemic, reduced incidence of many viral and
bacterial infections has been reported in children: bronchiolitis, varicella, measles, pertussis …
bacterial infections has been reported in children: bronchiolitis, varicella, measles, pertussis …
Bronchiolitis
SR Dalziel, L Haskell, S O'Brien, ML Borland, AC Plint… - The Lancet, 2022 - thelancet.com
Viral bronchiolitis is the most common cause of admission to hospital for infants in high-
income countries. Respiratory syncytial virus accounts for 60–80% of bronchiolitis …
income countries. Respiratory syncytial virus accounts for 60–80% of bronchiolitis …
Prefusion F protein–based respiratory syncytial virus immunization in pregnancy
Background Respiratory syncytial virus (RSV), a major cause of illness and death in infants
worldwide, could be prevented by vaccination during pregnancy. The efficacy …
worldwide, could be prevented by vaccination during pregnancy. The efficacy …