Inhibition of protein misfolding and aggregation by natural phenolic compounds
Protein misfolding and aggregation into fibrillar deposits is a common feature of a large
group of degenerative diseases affecting the central nervous system or peripheral organs …
group of degenerative diseases affecting the central nervous system or peripheral organs …
Nanomaterials in bone regeneration
V Babuska, PB Kasi, P Chocholata, L Wiesnerova… - Applied Sciences, 2022 - mdpi.com
Nanomaterials are promising in the development of innovative therapeutic options that
include tissue and organ replacement, as well as bone repair and regeneration. The …
include tissue and organ replacement, as well as bone repair and regeneration. The …
Non-enzymatic glycation of protein induces cancer cell proliferation and its inhibition by quercetin: Spectroscopic, cytotoxicity and molecular docking studies
Methylglyoxal (MG) is a potent glycating agent which reacts with proteins to form advanced
glycation end products (AGEs). These chemically stable AGEs crosslink with proteins and …
glycation end products (AGEs). These chemically stable AGEs crosslink with proteins and …
Inhibition of protein misfolding and aggregation by steroidal quinoxalin-2 (1H)-one and their molecular docking studies
A series of D-ring fused 16-substituted steroidal quinoxalin-2 (1H)-one attached to an
electron-releasing (ER) or electron-withdrawing (EW) groups via steroidal oxoacetate …
electron-releasing (ER) or electron-withdrawing (EW) groups via steroidal oxoacetate …
Cyanidin 3-rutinoside defibrillated bovine serum albumin under the glycation-promoting conditions: A study with multispectral, microstructural, and computational …
Findings small molecules with protein disaggregation effects are lately needed. For the first
time, we studied the in vitro-antifibrillogenic effects of cyanidin 3-rutinoside (C3R), purified …
time, we studied the in vitro-antifibrillogenic effects of cyanidin 3-rutinoside (C3R), purified …
Inhibition of amyloid-like fibril formation of trypsin by red wines
M Kotormán, PB Kasi, L Halasz… - Protein and Peptide …, 2017 - ingentaconnect.com
The aim of the present study was to examine the potential role and applicability of dietary
supplements in reducing the risk of development of amyloid diseases associated with the …
supplements in reducing the risk of development of amyloid diseases associated with the …
Investigating the preventive effects of baicalin and gallocatechin against glyoxal-induced cystatin aggregation
Several mammalian proteins form pathological deposits under nonphysiological conditions
that are associated with many degenerative diseases. Protein aggregation is associated …
that are associated with many degenerative diseases. Protein aggregation is associated …
Among commercially available fruit juices, pomegranate is the most effective inhibitor of PMS-trypsin amyloid-like fibrils formation
PB Kasi, M Kotormán - Natural Product Communications, 2019 - journals.sagepub.com
The formation of amyloid fibrils is associated with many human illnesses, such as
Alzheimer's, Huntington's, and Parkinson's diseases, amyotrophic lateral sclerosis …
Alzheimer's, Huntington's, and Parkinson's diseases, amyotrophic lateral sclerosis …
Spectroscopic evaluation of the interaction between pesticides and chickpea cystatin: comparative binding and toxicity analyses
The binding study of pesticides with proteins is of great importance in ecotoxicology. In this
study, a comparative interaction mechanism of phytocystatin with three pesticides has been …
study, a comparative interaction mechanism of phytocystatin with three pesticides has been …
Mycobacterium tuberculosis low molecular weight T‐cell antigen Mtb8.4 has heme‐binding and fiber‐forming properties
Mtb8. 4, a secretory T‐cell antigen of Mycobacterium tuberculosis, is important for providing
an antigen‐specific immune response. In this study, we showed Mtb8. 4 to have both heme …
an antigen‐specific immune response. In this study, we showed Mtb8. 4 to have both heme …