Anti‐nerve growth factor monoclonal antibodies for the control of pain in dogs and cats

M Enomoto, PW Mantyh, J Murrell, JF Innes… - Veterinary …, 2019 - Wiley Online Library
Nerve growth factor (NGF) is essential for the survival of sensory and sympathetic neurons
during development. However, in the adult, NGF and its interaction with tropomyosin …

2022 AAHA pain management guidelines for dogs and cats

ME Gruen, BDX Lascelles… - Journal of the …, 2022 - meridian.allenpress.com
These updated guidelines present a practical and logical approach to the assessment and
management of acute and chronic pain in canine and feline patients. Recognizing pain is …

Assessment of quality of life and chronic pain in dogs

Z Belshaw, J Yeates - The Veterinary Journal, 2018 - Elsevier
Assessment of chronic pain and quality of life (QOL) are integral to clinical veterinary
research and practice, and recent years have seen an increase in the published tools …

2022 AAFP/ISFM cat friendly veterinary interaction guidelines: approach and handling techniques

I Rodan, N Dowgray, HC Carney… - Journal of feline …, 2022 - journals.sagepub.com
Practical relevance: The '2022 AAFP/ISFM Cat Friendly Veterinary Interaction Guidelines:
Approach and Handling Techniques'(hereafter the 'Cat Friendly Veterinary Interaction …

2021 AAFP feline senior care guidelines

M Ray, HC Carney, B Boynton… - Journal of Feline …, 2021 - journals.sagepub.com
The '2021 AAFP Feline Senior Care Guidelines' are authored by a Task Force of experts in
feline clinical medicine and serve as an update and extension of those published in 2009 …

Frunevetmab, a felinized anti‐nerve growth factor monoclonal antibody, for the treatment of pain from osteoarthritis in cats

ME Gruen, JAE Myers, JKS Tena… - Journal of Veterinary …, 2021 - Wiley Online Library
Background Frunevetmab, a felinized antinerve growth factor monoclonal antibody,
effectively decreases osteoarthritis (OA) pain in cats. Objective To evaluate the efficacy of …

2024 ISFM and AAFP consensus guidelines on the long-term use of NSAIDs in cats

S Taylor, M Gruen, K KuKanich… - Journal of Feline …, 2024 - journals.sagepub.com
Practical relevance: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and
are effective for the management of pain in cats. These Guidelines will support veterinarians …

Behavioural signs of pain in cats: an expert consensus

I Merola, DS Mills - PloS one, 2016 - journals.plos.org
Objectives To identify where a consensus can be reached between veterinary experts in
feline medicine on the core signs sufficient for pain (sufficient to indicate pain when they …

Caregiver placebo effect in analgesic clinical trials for cats with naturally occurring degenerative joint disease‐associated pain

ME Gruen, DC Dorman, BDX Lascelles - Veterinary Record, 2017 - Wiley Online Library
A literature review identified six placebo‐controlled studies of analgesics in client‐owned
cats with degenerative joint disease‐associated pain. Five studies with 96 cats had …

A feline‐specific anti‐nerve growth factor antibody improves mobility in cats with degenerative joint disease–associated pain: A pilot proof of concept study

ME Gruen, AE Thomson, EH Griffith… - Journal of veterinary …, 2016 - Wiley Online Library
Background Neutralizing antibodies against nerve growth factor (NGF) are analgesic in
rodent models, naturally occurring degenerative joint disease (DJD) pain in dogs, and …