Computational prediction of eukaryotic phosphorylation sites

B Trost, A Kusalik - Bioinformatics, 2011 - academic.oup.com
Motivation: Kinase-mediated phosphorylation is the central mechanism of post-translational
modification to regulate cellular responses and phenotypes. Signaling defects associated …

Approaches to study phosphatases

S Fahs, P Lujan, M Köhn - ACS chemical biology, 2016 - ACS Publications
Phosphatases play key roles in normal physiology and diseases. Studying phosphatases
has been both essential and challenging, and the application of conventional genetic and …

GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy

Y Xue, J Ren, X Gao, C **, L Wen, X Yao - Molecular & cellular proteomics, 2008 - ASBMB
Identification of protein phosphorylation sites with their cognate protein kinases (PKs) is a
key step to delineate molecular dynamics and plasticity underlying a variety of cellular …

iPhosT-PseAAC: Identify phosphothreonine sites by incorporating sequence statistical moments into PseAAC

YD Khan, N Rasool, W Hussain, SA Khan… - Analytical biochemistry, 2018 - Elsevier
Among all the post-translational modifications (PTMs) of proteins, Phosphorylation is known
to be the most important and highly occurring PTM in eukaryotes and prokaryotes. It has an …

Reprogramming the fatty acid metabolism of Yarrowia lipolytica to produce the customized omega-6 polyunsaturated fatty acids

J Wang, X Yu, K Wang, L Lin, HH Liu… - Bioresource …, 2023 - Elsevier
Omega-6 polyunsaturated fatty acids (ω6-PUFAs), such as γ-linolenic acid (GLA), dihomo-γ-
linolenic acid (DGLA) and arachidonic acid (ARA), are indispensable nutrients for human …

Prediction of Ubiquitination Sites by Using the Composition of k-Spaced Amino Acid Pairs

Z Chen, YZ Chen, XF Wang, C Wang, RX Yan… - PloS one, 2011 - journals.plos.org
As one of the most important reversible protein post-translation modifications, ubiquitination
has been reported to be involved in lots of biological processes and closely implicated with …

iPhosH-PseAAC: Identify phosphohistidine sites in proteins by blending statistical moments and position relative features according to the Chou's 5-step rule and …

M Awais, W Hussain, YD Khan… - … ACM transactions on …, 2019 - ieeexplore.ieee.org
Protein phosphorylation is one of the key mechanism in prokaryotes and eukaryotes and is
responsible for various biological functions such as protein degradation, intracellular …

The PhosphoGRID Saccharomyces cerevisiae protein phosphorylation site database: version 2.0 update

I Sadowski, BJ Breitkreutz, C Stark, TC Su… - Database, 2013 - academic.oup.com
PhosphoGRID is an online database that curates and houses experimentally verified in vivo
phosphorylation sites in the Saccharomyces cerevisiae proteome (www. phosphogrid. org) …

High‐accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast

F Gnad, LMF de Godoy, J Cox, N Neuhauser… - …, 2009 - Wiley Online Library
Protein phosphorylation is a fundamental regulatory mechanism that affects many cell
signaling processes. Using high‐accuracy MS and stable isotope labeling in cell culture …

[LLIBRE][B] Machine learning approaches to bioinformatics

ZR Yang - 2010 - books.google.com
1. Introduction. 1.1. Brief history of bioinformatics. 1.2. Database application in
bioinformatics. 1.3. Web tools and services for sequence homology alignment. 1.4. Pattern …