Regulation of microRNA function in animals
Since their serendipitous discovery in nematodes, microRNAs (miRNAs) have emerged as
key regulators of biological processes in animals. These small RNAs form complex networks …
key regulators of biological processes in animals. These small RNAs form complex networks …
The rise of regulatory RNA
Discoveries over the past decade portend a paradigm shift in molecular biology. Evidence
suggests that RNA is not only functional as a messenger between DNA and protein but also …
suggests that RNA is not only functional as a messenger between DNA and protein but also …
Diversifying microRNA sequence and function
MicroRNAs (miRNAs) regulate the expression of most genes in animals, but we are only
now beginning to understand how they are generated, assembled into functional complexes …
now beginning to understand how they are generated, assembled into functional complexes …
MicroRNA: biogenesis, function and role in cancer
LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …
The epigenetics of aging and neurodegeneration
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …
expression that do not involve changes in the genotype. Epigenetics is of increasing …
MicroRNAs in development and disease
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …
Many roads to maturity: microRNA biogenesis pathways and their regulation
J Winter, S Jung, S Keller, RI Gregory… - Nature cell biology, 2009 - nature.com
MicroRNAs are important regulators of gene expression that control both physiological and
pathological processes such as development and cancer. Although their mode of action has …
pathological processes such as development and cancer. Although their mode of action has …
A brief review on the mechanisms of miRNA regulation
MicroRNAs (miRNAs) are a class of short, endogenously-initiated non-coding RNAs that
post-transcriptionally control gene expression via either translational repression or mRNA …
post-transcriptionally control gene expression via either translational repression or mRNA …
Evolution of microRNA diversity and regulation in animals
E Berezikov - Nature Reviews Genetics, 2011 - nature.com
In the past decade, microRNAs (miRNAs) have been uncovered as key regulators of gene
expression at the post-transcriptional level. The ancient origin of miRNAs, their dramatic …
expression at the post-transcriptional level. The ancient origin of miRNAs, their dramatic …
Functions and regulation of RNA editing by ADAR deaminases
K Nishikura - Annual review of biochemistry, 2010 - annualreviews.org
One type of RNA editing converts adenosines to inosines (A→ I editing) in double-stranded
RNA (dsRNA) substrates. A→ I RNA editing is mediated by adenosine deaminase acting on …
RNA (dsRNA) substrates. A→ I RNA editing is mediated by adenosine deaminase acting on …