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CRISPR/Cas: a Nobel Prize award-winning precise genome editing technology for gene therapy and crop improvement
Since it was first recognized in bacteria and archaea as a mechanism for innate viral
immunity in the early 2010s, clustered regularly interspaced short palindromic repeats …
immunity in the early 2010s, clustered regularly interspaced short palindromic repeats …
Signal amplification and output of CRISPR/Cas-based biosensing systems: A review
SY Wang, YC Du, DX Wang, JY Ma, AN Tang… - Analytica Chimica …, 2021 - Elsevier
CRISPR (clustered regularly interspaced short palindromic repeats)/Cas (CRISPR-
associated) proteins are powerful gene-editing tools because of their ability to accurately …
associated) proteins are powerful gene-editing tools because of their ability to accurately …
A one-pot CRISPR/Cas13a-based contamination-free biosensor for low-cost and rapid nucleic acid diagnostics
F Hu, Y Liu, S Zhao, Z Zhang, X Li, N Peng… - Biosensors and …, 2022 - Elsevier
The pandemic due to the outbreak of 2019 coronavirus disease (COVID-19) caused by
novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has raised significant …
novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has raised significant …
Efficient, rapid, and sensitive detection of plant RNA viruses with one-pot RT-RPA–CRISPR/Cas12a assay
Most viruses that infect plants use RNA to carry their genomic information; timely and robust
detection methods are crucial for efficient control of these diverse pathogens. The RNA …
detection methods are crucial for efficient control of these diverse pathogens. The RNA …
Emerging technologies revolutionising disease diagnosis and monitoring in aquatic animal health
In recent years, aquaculture has seen tremendous growth worldwide due to technological
advancements, leading to research and development of various innovations. Aquaculture …
advancements, leading to research and development of various innovations. Aquaculture …
Pyrococcus furiosus Argonaute Combined with Recombinase Polymerase Amplification for Rapid and Sensitive Detection of Enterocytozoon hepatopenaei
L Yang, B Guo, Y Wang, C Zhao, X Zhang… - Journal of Agricultural …, 2022 - ACS Publications
Enterocytozoon hepatopenaei (EHP) is one of the most serious pathogens in shrimp
farming. This study combines recombinase polymerase amplification (RPA) with the …
farming. This study combines recombinase polymerase amplification (RPA) with the …
Development of CRISPR/Cas13a-based assays for the diagnosis of schistosomiasis
SR MacGregor, DP McManus, H Sivakumaran… - …, 2023 - thelancet.com
Background Schistosomiasis is a disease that significantly impacts human health in the
develo** world. Effective diagnostics are urgently needed for improved control of this …
develo** world. Effective diagnostics are urgently needed for improved control of this …
Applications of the versatile CRISPR‐Cas13 RNA targeting system
M Kordyś, R Sen, Z Warkocki - Wiley Interdisciplinary Reviews …, 2022 - Wiley Online Library
CRISPR‐Cas are adaptable natural prokaryotic defense systems that act against invading
viruses and plasmids. Among the six currently known major CRISPR‐Cas types, the type VI …
viruses and plasmids. Among the six currently known major CRISPR‐Cas types, the type VI …
The shrimp microsporidian Enterocytozoon hepatopenaei (EHP): Biology, pathology, diagnostics and control
T Chaijarasphong, N Munkongwongsiri… - Journal of invertebrate …, 2021 - Elsevier
Disease is a major limiting factor in the global production of cultivated shrimp. The
microsporidian parasite Enterocytozoon hepatopenaei (EHP) was formally characterized in …
microsporidian parasite Enterocytozoon hepatopenaei (EHP) was formally characterized in …
From the basics to emerging diagnostic technologies: What is on the horizon for tilapia disease diagnostics?
Tilapia is an affordable protein source farmed in over 140 countries with the majority of
production in low‐and middle‐income countries. Intensification of tilapia farming has …
production in low‐and middle‐income countries. Intensification of tilapia farming has …