[HTML][HTML] A comprehensive review on modeling aspects of infusion-based drug delivery in the brain

T Yuan, W Zhan, M Terzano, GA Holzapfel, D Dini - Acta Biomaterialia, 2024 - Elsevier
Brain disorders represent an ever-increasing health challenge worldwide. While
conventional drug therapies are less effective due to the presence of the blood-brain barrier …

Recent advances in soft biological tissue manipulating technologies

Z Liu, Z Liao, D Wang, C Wang, C Song, H Li… - Chinese journal of …, 2022 - Springer
Biological soft tissues manipulation, including conventional (mechanical) and
nonconventional (laser, waterjet and ultrasonic) processes, is critically required in most …

[HTML][HTML] Insights into the mechanics of solid conical microneedle array insertion into skin using the finite element method

W Shu, H Heimark, N Bertollo, DJ Tobin… - Acta Biomaterialia, 2021 - Elsevier
In order to develop optimum microneedle designs, researchers must first develop robust,
repeatable and adaptable test methods which are representative of in vivo conditions …

Additive manufacturing of honeybee-inspired microneedle for easy skin insertion and difficult removal

Z Chen, Y Lin, W Lee, L Ren, B Liu… - … applied materials & …, 2018 - ACS Publications
With natural evolution, honeybee stinger with microbarbs can easily penetrate and trap in
the skin of hostile animals to inject venom for self-defense. We proposed a novel three …

A lubricated nonimmunogenic neural probe for acute insertion trauma minimization and long‐term signal recording

Y Lee, H Shin, D Lee, S Choi, IJ Cho… - Advanced Science, 2021 - Wiley Online Library
Brain‐machine interfaces (BMIs) that link the brain to a machine are promising for the
treatment of neurological disorders through the bi‐directional translation of neural …

[HTML][HTML] Modelling and experimental characterisation of the rate dependent fracture properties of gelatine gels

AE Forte, F D'amico, MN Charalambides, D Dini… - Food …, 2015 - Elsevier
The mechanical behaviour of gelatine gels as a function of test rate and gelatine
concentration was determined through lubricated uniaxial compression and wire cutting …

Soft tissue phantoms for realistic needle insertion: a comparative study

A Leibinger, AE Forte, Z Tan, MJ Oldfield… - Annals of biomedical …, 2016 - Springer
Phantoms are common substitutes for soft tissues in biomechanical research and are
usually tuned to match tissue properties using standard testing protocols at small strains …

Digital rock analysis to estimate stress-sensitive rock permeabilities

F Al Balushi, AD Taleghani - Computers and Geotechnics, 2022 - Elsevier
Reservoir deformations due to stress changes may have a substantial impact on the
effective flow properties of reservoir rocks, which may potentially impact productivity and …

Modelling biological puncture: a mathematical framework for determining the energetics and scaling

B Zhang, PSL Anderson - Journal of the Royal Society …, 2022 - royalsocietypublishing.org
Biological puncture systems use a diversity of morphological tools (stingers, teeth, spines
etc.) to penetrate target tissues for a variety of functions (prey capture, defence …

Structures, properties, and functions of the stings of honey bees and paper wasps: a comparative study

ZL Zhao, HP Zhao, GJ Ma, CW Wu, K Yang… - Biology …, 2015 - journals.biologists.com
Through natural selection, many animal organs with similar functions have evolved different
macroscopic morphologies and microscopic structures. Here, we comparatively investigate …