After 50 years of vibrational circular dichroism spectroscopy: Challenges and opportunities of increasingly accurate and complex experiments and computations

J Bloino, S Jähnigen, C Merten - The Journal of Physical …, 2024 - ACS Publications
VCD research continues to thrive, driven by ongoing experimental and theoretical advances.
Modern studies deal with increasingly complex samples featuring weak intermolecular …

How Crystal Symmetry Dictates Non‐Local Vibrational Circular Dichroism in the Solid State

S Jähnigen, K Le Barbu‐Debus… - Angewandte Chemie …, 2023 - Wiley Online Library
Abstract Solid‐State Vibrational Circular Dichroism (VCD) can be used to determine the
absolute structure of chiral crystals, but its interpretation remains a challenge in modern …

Anharmonic Aspects in Vibrational Circular Dichroism Spectra from 900 to 9000 cm–1 for Methyloxirane and Methylthiirane

M Fusè, G Longhi, G Mazzeo, S Stranges… - The Journal of …, 2022 - ACS Publications
Vibrational circular dichroism (VCD) spectra and the corresponding IR spectra of the chiral
isomers of methyloxirane and of methylthiirane have been reinvestigated, both …

[HTML][HTML] Anharmonic DFT study of near-infrared spectra of caffeine: Vibrational analysis of the second overtones and ternary combinations

J Grabska, KB Beć, Y Ozaki, CW Huck - Molecules, 2021 - mdpi.com
Anharmonic quantum chemical calculations were employed to simulate and interpret a near-
infrared (NIR) spectrum of caffeine. First and second overtones, as well as binary and …

Solvent effects and aggregation phenomena studied by vibrational optical activity and molecular dynamics: the case of pantolactone

S Ghidinelli, S Abbate, J Koshoubu… - The Journal of …, 2020 - ACS Publications
Raman and Raman optical activity (ROA), IR, and vibrational circular dichroism (VCD)
spectra of (R)-and (S)-pantolactone have been recorded in three solvents. ROA has been …

Theoretical simulation of near-infrared spectrum of piperine: insight into band origins and the features of regression models

J Grabska, KB Beć, S Mayr… - Applied Spectroscopy, 2021 - journals.sagepub.com
We investigated the near-infrared spectrum of piperine using quantum mechanical
calculations. We evaluated two efficient approaches, DVPT2//PM6 and DVPT2//ONIOM …

Mid‐IR and CH stretching vibrational circular dichroism spectroscopy to distinguish various sources of chirality: The case of quinophaneoxazoline based ruthenium (II) …

M Fusè, G Mazzeo, S Abbate, R Ruzziconi, J Bloino… - Chirality, 2024 - Wiley Online Library
Five diastereomers of ruthenium (II) complexes based on quinolinophaneoxazoline ligands
were investigated by vibrational circular dichroism (VCD) in the mid‐IR and CH stretching …

Anharmonic vibrational raman optical activity of methyloxirane: Theory and experiment pushed to the limits

Q Yang, J Kapitán, P Bour, J Bloino - The Journal of Physical …, 2022 - ACS Publications
Combining Raman scattering and Raman optical activity (ROA) with computer simulations
reveals fine structural and physicochemical properties of chiral molecules. Traditionally, the …

[HTML][HTML] Pushing measurements and interpretation of VCD spectra in the IR, NIR and visible ranges to the detectability and computational complexity limits

M Fusè, G Mazzeo, J Bloino, G Longhi… - Spectrochimica Acta Part …, 2024 - Elsevier
Abstract (R)-Limonene VCD and IR absorption spectra for neat liquid samples are
considered from 900 to 16,000 cm− 1, using mostly data by Nafie et al. up to 10,000 cm− 1 …

Basis set dependence of S [double bond, length as m-dash] O stretching frequencies and its consequences for IR and VCD spectra predictions

K Scholten, E Engelage, C Merten - Physical Chemistry Chemical …, 2020 - pubs.rsc.org
Benchmarking functionals and basis sets for the computational prediction of molecular
properties is usually done on very small model systems. Larger organic molecules …