There is a growing body of scientific research showing the link between depression and
dementia in Alzheimer's disease (AD). The chronic stress contributes to the formation of …

Alzheimer disease (AD) is associated with multiple etiologies and pathological mechanisms,
among which oxidative stress (OS) appears as a major determinant. Intriguingly, OS arises …

The ketogenic diet (KD) is a high-fat, low-carbohydrate and adequate-protein diet that has
gained popularity in recent years in the context of neurological diseases (NDs). The …

Inheritance of apolipoprotein E4 (APOE4) is a major risk factor for development of
Alzheimer's disease (AD). This lipoprotein, in contrast to apoE2, has arginine residues at …

Despite more than a century of research, the aetiology of sporadic Alzheimer's disease (AD)
remains unclear and finding disease modifying treatments for AD presents one of the …

Featured Application Utilization of Rosmarinus officinalis extracts and/or its bioactives as
ingredients in functional products, foods, cosmetics, and pharmaceuticals, with anti …

Abstract The Apolipoprotein E ε4 (ApoE ε4) allele, encoding ApoE4, is the strongest genetic
risk factor for late-onset Alzheimer's disease (LOAD). Emerging epidemiological evidence …

The APOE gene encoding the Apolipoprotein E protein is the single most significant genetic
risk factor for late‐onset Alzheimer's disease. The APOE4 genotype confers a significantly …

Neurodegenerative diseases are typified by neuronal loss associated with progressive
dysfunction and clinical presentation. Neurodegenerative diseases are characterized by the …

Computational systems biology aims at integrating biology and computational methods to
gain a better understating of biological phenomena. It often requires the assistance of global …