Bacteria possess an extraordinary repertoire of cell envelope glycans that have critical
physiological functions. Pathogenic bacteria have glycans that are essential for growth and …

A fluorescence turn-on probe, an azide-masked and trehalose-derivatized carbazole (Tre-
Cz), was developed to image mycobacteria. The fluorescence turn-on is achieved by …

The disaccharide trehalose is essential for viability of Mycobacterium tuberculosis, which
synthesizes trehalose de novo but can also utilize exogenous trehalose. The mycobacterial …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is the leading cause of
death worldwide by infectious disease. Treatment of Mtb infection requires a six-month …

Tuberculosis (TB) remains one of the leading infectious causes of death worldwide.
Detecting and precisely quantifying viable Mycobacterium tuberculosis (M. tuberculosis) is …

A new practical, catalytic, and highly stereoselective method for directly accessing 1, 1-α,
α′-linked 2-deoxy trehalose analogues via AuCl3-catalyzed dehydrative glycosylation …

Trehalose, a disaccharide of glucose, is increasingly recognized as an important contributor
to virulence in major bacterial pathogens, such as Mycobacterium tuberculosis …

The Mycobacterium tuberculosis (Mtb) LpqY-SugABC ATP-binding cassette transporter is a
recycling system that imports trehalose released during remodeling of the Mtb cell-envelope …

Bacteriophages have many biotechnological and therapeutic applications, but as with other
biologics, cryopreservation is essential for storage and distribution. Macromolecular …

Trehalose-based probes are useful tools that allow the detection of the mycomembrane of
mycobacteria through the metabolic labeling approach. Trehalose analogues conjugated to …