The finding that animals with circadian gene mutations exhibit diet-induced obesity and
metabolic syndrome with hypoinsulinemia revealed a distinct role for the clock in the brain …

With the aging world population, the prevalence of aging‐related disorders is on the rise.
Diseases such as Alzheimer's, type 2 diabetes mellitus (T2DM), Parkinson's …

Muscle isometric torque fluctuates according to time-of-day with such variation owed to the
influence of circadian molecular clock genes. Satellite cells (SCs), the muscle stem cell …

Introduction High-altitude pulmonary edema (HAPE) is a severe and potentially fatal
condition with limited treatment options. Although ceramide kinase (CERK)-derived …

Adult stem cells maintain homeostasis and enable regeneration of most tissues.
Quiescence, proliferation, and differentiation of stem cells and their progenitors are tightly …

Sarcopenia is an age-related condition that involves a progressive decline in muscle mass
and function, leading to increased risk of falls, frailty, and mortality. Although the exact …

Cigarette smoke (CS) is the major risk factor for chronic obstructive pulmonary disease
(COPD), and sarcopenia is one of the significant comorbidities of COPD. However, the …

Skeletal muscle comprises approximately 50% of individual body mass and plays vital roles
in locomotion, heat production, and whole body metabolic homeostasis. This tissue exhibits …

The circadian clock system, an evolutionarily conserved mechanism, orchestrates diurnal
rhythms in biological activities such as behavior and metabolism, aligning them with the …

Background Resistance exercise leads to improved muscle function and metabolic
homeostasis. Yet how circadian rhythm impacts exercise outcomes and its molecular …