RAS and MYC rank amongst the most commonly altered oncogenes in cancer, with RAS
being the most frequently mutated and MYC the most amplified. The cooperative interplay …

Researchers are amazed at the multitude of biological effects of 3′, 4′, 5, 7-
tetrahydroxyflavone, more commonly known as luteolin, as it simultaneously has antioxidant …

Drug resistance is a principal limitation to the long-term efficacy of cancer therapies. Cancer
genome sequencing can retrospectively delineate the genetic basis of drug resistance, but …

Non-small cell lung cancer (NSCLC) and colorectal cancer (CRC) are associated with a
high mortality rate. Mutations in the V-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog …

Background Autologous tumor cell-based vaccines (ATVs) aim to prevent and treat tumor
metastasis by activating patient-specific tumor antigens to induce immune memory …

Introduction Inflammation plays a significant role in various cancers, including lung cancer,
where the inflammatory cytokine IL-1β is often elevated in the tumor microenvironment …

Simple Summary Colorectal cancer (CRC) is a deadly disease in which KRAS mutations are
prevalent and are associated with poor prognosis. The emergence of KRAS inhibitors is a …

Luteolin is a flavonoid widely found in plants, including vegetables, botanical drugs, and
fruits. Owing to its diverse pharmacological activities, such as anticancer, oxidative stress …

Histone chaperones are integral to chromatin dynamics, facilitating the assembly and
disassembly of nucleosomes, thereby playing a crucial role in regulating gene expression …

The biological heterogeneity of colorectal cancer makes its molecular characteristics
essential for therapeutic decision-making and prognostic evaluation. Recent advancements …