[HTML][HTML] Exploring the role of neuroplasticity in development, aging, and neurodegeneration
Neuroplasticity refers to the ability of the brain to reorganize and modify its neural
connections in response to environmental stimuli, experience, learning, injury, and disease …
connections in response to environmental stimuli, experience, learning, injury, and disease …
Physiology of astroglia
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …
types with specific spatial distribution patterns and structural and functional properties …
AgRP/NPY and POMC neurons in the arcuate nucleus and their potential role in treatment of obesity
Obesity is a major health crisis affecting over a third of the global population. This
multifactorial disease is regulated via interoceptive neural circuits in the brain, whose …
multifactorial disease is regulated via interoceptive neural circuits in the brain, whose …
Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
It has been proposed that the hypothalamus helps to control ageing, but the mechanisms
responsible remain unclear. Here we develop several mouse models in which hypothalamic …
responsible remain unclear. Here we develop several mouse models in which hypothalamic …
Single-cell RNA-seq reveals hypothalamic cell diversity
The hypothalamus is one of the most complex brain structures involved in homeostatic
regulation. Defining cell composition and identifying cell-type-specific transcriptional …
regulation. Defining cell composition and identifying cell-type-specific transcriptional …
Beyond the hippocampus and the SVZ: adult neurogenesis throughout the brain
Convincing evidence has repeatedly shown that new neurons are produced in the
mammalian brain into adulthood. Adult neurogenesis has been best described in the …
mammalian brain into adulthood. Adult neurogenesis has been best described in the …
The cellular and molecular bases of leptin and ghrelin resistance in obesity
Obesity, a major risk factor for the development of diabetes mellitus, cardiovascular diseases
and certain types of cancer, arises from a chronic positive energy balance that is often due to …
and certain types of cancer, arises from a chronic positive energy balance that is often due to …
Obesity-induced inflammation: connecting the periphery to the brain
Obesity is often associated with a chronic, low-grade inflammatory state affecting the entire
body. This sustained inflammatory state disrupts the coordinated communication between …
body. This sustained inflammatory state disrupts the coordinated communication between …
Application of human brain organoids—opportunities and challenges in modeling human brain development and neurodevelopmental diseases
S Kim, MY Chang - International journal of molecular sciences, 2023 - mdpi.com
Brain organoids are three-dimensional (3D) structures derived from human pluripotent stem
cells (hPSCs) that reflect early brain organization. These organoids contain different cell …
cells (hPSCs) that reflect early brain organization. These organoids contain different cell …