Dendritic cells: from ontogenetic orphans to myelomonocytic descendants
JH Peters, R Gieseler, B Thiele, F Steinbach - Immunology today, 1996 - Elsevier
Although dendritic cells (DCs) and macrophages share a bone marrow origin, these cells
were long assumed to differentiate via discrete pathways. DCs have now been clearly …
were long assumed to differentiate via discrete pathways. DCs have now been clearly …
Adoptive immunotherapy of cancer using monocyte-derived macrophages: rationale, current status, and perspectives
R Andreesen, B Hennemann… - Journal of leukocyte …, 1998 - academic.oup.com
Adoptive transfer of host defense cells may be able to correct an otherwise defective
generation of competent immune cells in patients with cancer. Ex vivo-grown cytotoxic …
generation of competent immune cells in patients with cancer. Ex vivo-grown cytotoxic …
Enhancement of antitumor immunity by CTLA-4 blockade
DR Leach, MF Krummel, JP Allison - Science, 1996 - science.org
One reason for the poor immunogenicity of many tumors may be that they cannot provide
signals for CD28-mediated costimulation necessary to fully activate T cells. It has recently …
signals for CD28-mediated costimulation necessary to fully activate T cells. It has recently …
Vaccination of melanoma patients with peptide-or tumorlysate-pulsed dendritic cells
Melanoma is the main cause of death in patients with skin cancer1. Cytotoxic T lymphocytes
(CTLs) attack melanoma cells in an HLA-restricted and tumor antigen-specific manner …
(CTLs) attack melanoma cells in an HLA-restricted and tumor antigen-specific manner …
Engineered nucleic acids encoding a modified erythropoietin and their expression
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Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells
L Piemonti, P Monti, M Sironi, P Fraticelli… - The Journal of …, 2000 - journals.aai.org
We studied the effects of 1α, 25-dihydroxyvitamin D 3 (1α, 25-(OH) 2 D 3) on differentiation,
maturation, and functions of dendritic cells (DC) differentiated from human monocytes in vitro …
maturation, and functions of dendritic cells (DC) differentiated from human monocytes in vitro …
Terminally modified RNA
T Chakraborty, S Bancel, SG Hoge, A Roy… - US Patent …, 2017 - Google Patents
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Engineered nucleic acids and methods of use thereof
NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C (= O) C (NC (= O)
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
C (CCC (N)= O) NC (= O) C (CCC (O)= O) NC (= O) C (C (C) C) NC (= O) C (NC (= O) CN) C …
Modified polynucleotides for the production of biologics and proteins associated with human disease
S Bancel, T Chakraborty, A De Fougerolles… - US Patent …, 2015 - Google Patents
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Modified polynucleotides for the production of secreted proteins
T Chakraborty, A De Fougerolles - US Patent 9,192,651, 2015 - Google Patents
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