Pyrrole: An emerging scaffold for construction of valuable therapeutic agents

SS Gholap - European journal of medicinal chemistry, 2016 - Elsevier
Pyrrole derivatives comprise a class of biologically active heterocyclic compounds which
can serve as promising scaffolds for antimicrobial, antiviral, antimalarial, antitubercular, anti …

The role of natural products in drug discovery and development against neglected tropical diseases

PM Cheuka, G Mayoka, P Mutai, K Chibale - Molecules, 2016 - mdpi.com
Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in develo** …

Marine pharmacology in 2009–2011: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral …

AMS Mayer, AD Rodríguez, O Taglialatela-Scafati… - Marine drugs, 2013 - mdpi.com
The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this
review, following the format used in the 1998–2008 reviews of this series. The …

Antiplasmodial natural products: an update

N Tajuddeen, FR Van Heerden - Malaria journal, 2019 - Springer
Background Malaria remains a significant public health challenge in regions of the world
where it is endemic. An unprecedented decline in malaria incidences was recorded during …

Marine pyrrole alkaloids

K Seipp, L Geske, T Opatz - Marine Drugs, 2021 - mdpi.com
Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal
intriguing structures. They are not only widespread in terrestrial habitats but can also …

Fruitful decade for antileishmanial compounds from 2002 to late 2011

H Hussain, A Al-Harrasi, A Al-Rawahi, IR Green… - Chemical …, 2014 - ACS Publications
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …

Use of chiral auxiliaries in the asymmetric synthesis of biologically active compounds: A review

G Diaz‐Muñoz, IL Miranda, SK Sartori… - Chirality, 2019 - Wiley Online Library
This review article describes the use of some of the most popular chiral auxiliaries in the
asymmetric synthesis of biologically active compounds. Chiral auxiliaries derived from …

Biosynthesis, asymmetric synthesis, and pharmacology, including cellular targets, of the pyrrole-2-aminoimidazole marine alkaloids

A Al-Mourabit, MA Zancanella, S Tilvi… - Natural product reports, 2011 - pubs.rsc.org
Covering: up to February 2011 The pyrrole-2-aminoimidazole (P-2-AI) alkaloids are a
growing family of marine alkaloids, now numbering well over 150 members, with high …

Antiplasmodial natural products

CR Nogueira, LMX Lopes - Molecules, 2011 - mdpi.com
Malaria is a human infectious disease that is caused by four species of Plasmodium. It is
responsible for more than 1 million deaths per year. Natural products contain a great variety …

Muscarine, imidaozle, oxazole and thiazole alkaloids

Z ** - Natural Product Reports, 2013 - pubs.rsc.org
Covering: July 2010 to June 2012. Previous review: Nat. Prod. Rep., 2011, 28, 1143–1191.
Structurally diverse alkaloids containing five-membered heterocyclic subunits, such as …