Nicotine in inflammatory diseases: anti-inflammatory and pro-inflammatory effects

W Zhang, H Lin, M Zou, Q Yuan, Z Huang… - Frontiers in …, 2022 - frontiersin.org
As an anti-inflammatory alkaloid, nicotine plays dual roles in treating diseases. Here we
reviewed the anti-inflammatory and pro-inflammatory effects of nicotine on inflammatory …

Cigarette smoke-induced respiratory response: insights into cellular processes and biomarkers

SR Cha, J Jang, SM Park, SM Ryu, SJ Cho, SR Yang - Antioxidants, 2023 - mdpi.com
Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ
diseases owing to its high content of harmful chemicals and reactive oxygen species (ROS) …

[PDF][PDF] One year in review 2018: pathogenesis of rheumatoid arthritis

E Calabresi, F Petrelli, AF Bonifacio… - Clin Exp …, 2018 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that primarily
affects joints. The several mechanisms involved in the development of the disease are not …

Environmental exposures and autoimmune diseases: contribution of gut microbiome

MF Khan, H Wang - Frontiers in immunology, 2020 - frontiersin.org
Environmental agents have been gaining more attention in recent years for their role in the
pathogenesis of autoimmune diseases (ADs). Increasing evidence has linked environmental …

[HTML][HTML] The impact of cigarette smoking on risk of rheumatoid arthritis: a narrative review

Y Ishikawa, C Terao - Cells, 2020 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation
and subsequent proliferation of synovial tissues, which eventually leads to cartilage and …

A novel CD4+ CTL subtype characterized by chemotaxis and inflammation is involved in the pathogenesis of Graves' orbitopathy

Y Wang, Z Chen, T Wang, H Guo, Y Liu… - Cellular & molecular …, 2021 - nature.com
Abstract Graves' orbitopathy (GO), the most severe manifestation of Graves' hyperthyroidism
(GH), is an autoimmune-mediated inflammatory disorder, and treatments often exhibit a low …

[HTML][HTML] Smoking and osteoimmunology: Understanding the interplay between bone metabolism and immune homeostasis

G **e, C Huang, S Jiang, H Li, Y Gao, T Zhang… - Journal of Orthopaedic …, 2024 - Elsevier
Smoking continues to pose a global threat to morbidity and mortality in populations. The
detrimental impact of smoking on health and disease includes bone destruction and immune …

Effects of cigarette smoke on immunity, neuroinflammation and multiple sclerosis

M Alrouji, A Manouchehrinia, B Gran… - Journal of …, 2019 - Elsevier
Cigarette smoking is the most prominent significant cause of death and morbidity. It is
recognised as a risk factor for a number of immune mediated, inflammatory diseases …

Survivin in autoimmune diseases

G Gravina, C Wasén, MJ Garcia-Bonete, M Turkkila… - Autoimmunity …, 2017 - Elsevier
Survivin is a protein functionally important for cell division, apoptosis, and possibly, for micro-
RNA biogenesis. It is an established marker of malignant cell transformation. In non …

Survivin a pivotal antiapoptotic protein in rheumatoid arthritis

P Zafari, A Rafiei, SA Esmaeili… - Journal of cellular …, 2019 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease, pathologically characterized by
lymphocyte infiltration of the synovial membrane that leads to chronic inflammation and …