Recent advances in contrast-enhanced photoacoustic imaging: overcoming the physical and practical challenges

W Choi, B Park, S Choi, D Oh, J Kim, C Kim - Chemical Reviews, 2023 - ACS Publications
For decades now, photoacoustic imaging (PAI) has been investigated to realize its potential
as a niche biomedical imaging modality. Despite its highly desirable optical contrast and …

The emerging role of photoacoustic imaging in clinical oncology

L Lin, LV Wang - Nature Reviews Clinical Oncology, 2022 - nature.com
Clinical oncology can benefit substantially from imaging technologies that reveal
physiological characteristics with multiscale observations. Complementing conventional …

Label-free intraoperative histology of bone tissue via deep-learning-assisted ultraviolet photoacoustic microscopy

R Cao, SD Nelson, S Davis, Y Liang, Y Luo… - Nature biomedical …, 2023 - nature.com
Obtaining frozen sections of bone tissue for intraoperative examination is challenging. To
identify the bony edge of resection, orthopaedic oncologists therefore rely on pre-operative …

[HTML][HTML] In vivo liver function reserve assessments in alcoholic liver disease by scalable photoacoustic imaging

T Sun, J Lv, X Zhao, W Li, Z Zhang, L Nie - Photoacoustics, 2023 - Elsevier
We present a rapid and high-resolution photoacoustic imaging method for evaluating the
liver function reserve (LFR). To validate its accuracy, we establish alcoholic liver disease …

Multifunctional microrobot with real-time visualization and magnetic resonance imaging for chemoembolization therapy of liver cancer

G Go, A Yoo, KT Nguyen, M Nan, BA Darmawan… - Science …, 2022 - science.org
Microrobots that can be precisely guided to target lesions have been studied for in vivo
medical applications. However, existing microrobots have challenges in vivo such as …

Functional photoacoustic imaging: from nano-and micro-to macro-scale

B Park, D Oh, J Kim, C Kim - Nano Convergence, 2023 - Springer
Functional photoacoustic imaging is a promising biological imaging technique that offers
such unique benefits as scalable resolution and imaging depth, as well as the ability to …

Massively parallel functional photoacoustic computed tomography of the human brain

S Na, JJ Russin, L Lin, X Yuan, P Hu, KB Jann… - Nature Biomedical …, 2022 - nature.com
Abstract Blood-oxygen-level-dependent (BOLD) functional magnetic resonance imaging of
the human brain requires bulky equipment for the generation of magnetic fields …

Label-free biomedical optical imaging

NT Shaked, SA Boppart, LV Wang, J Popp - Nature photonics, 2023 - nature.com
Label-free optical imaging employs natural and non-destructive approaches to visualize
biomedical samples for both biological assays and clinical diagnosis. At present, this field …

A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo

Z Wu, L Li, Y Yang, P Hu, Y Li, SY Yang, LV Wang… - Science robotics, 2019 - science.org
Recently, tremendous progress in synthetic micro/nanomotors in diverse environment has
been made for potential biomedical applications. However, existing micro/nanomotor …

Deep learning acceleration of multiscale superresolution localization photoacoustic imaging

J Kim, G Kim, L Li, P Zhang, JY Kim, Y Kim… - Light: science & …, 2022 - nature.com
A superresolution imaging approach that localizes very small targets, such as red blood
cells or droplets of injected photoacoustic dye, has significantly improved spatial resolution …