Contemporary studies have completely changed the view of brain immunity from envisioning
the brain as isolated and inaccessible to peripheral immune cells to an organ in close …

Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Age is a major nonmodifiable risk factor for ischemic stroke. Central nervous system-
associated macrophages (CAMs) are resident immune cells located along the brain …

The choroid plexus (CP) forming the blood–cerebrospinal fluid (B-CSF) barrier is among the
least studied structures of the central nervous system (CNS) despite its clinical importance …

Abstract Analysis of entire transparent rodent bodies after clearing could provide holistic
biological information in health and disease, but reliable imaging and quantification of …

The nervous and immune systems control whole-body homeostasis and respond to various
types of tissue injury, including stroke, in a coordinated manner. Cerebral ischaemia and …

Ischaemic stroke elicits a strong neuroinflammatory response, but the functional relevance
and therapeutic potential of neuroinflammation has only recently become apparent. In acute …

Understanding the relationship between infection and stroke has taken on new urgency in
the era of the coronavirus disease 2019 (COVID-19) pandemic. This association is not a …

The fine balance between the secretion, composition, volume and turnover of cerebrospinal
fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance …

The barrier between the blood and the ventricular cerebrospinal fluid (CSF) is located at the
choroid plexuses. At the interface between two circulating fluids, these richly vascularized …