Artificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases

FM De La Vega, S Chowdhury, B Moore, E Frise… - Genome Medicine, 2021 - Springer
Background Clinical interpretation of genetic variants in the context of the patient's
phenotype is becoming the largest component of cost and time expenditure for genome …

Scalable, ultra-fast, and low-memory construction of compacted de Bruijn graphs with Cuttlefish 2

J Khan, M Kokot, S Deorowicz, R Patro - Genome biology, 2022 - Springer
The de Bruijn graph is a key data structure in modern computational genomics, and
construction of its compacted variant resides upstream of many genomic analyses. As the …

MetaMeta: integrating metagenome analysis tools to improve taxonomic profiling

VC Piro, M Matschkowski, BY Renard - Microbiome, 2017 - Springer
Background Many metagenome analysis tools are presently available to classify sequences
and profile environmental samples. In particular, taxonomic profiling and binning methods …

DNA map** using processor-in-memory architecture

D Lavenier, JF Roy, D Furodet - 2016 IEEE International …, 2016 - ieeexplore.ieee.org
This paper presents the implementation of a map** algorithm on a new Processing-in-
Memory (PIM) architecture developed by UPMEM Company. UPMEM's solution consists in …

Hadoop MapReduce performance on SSDs for analyzing social networks

M Bakratsas, P Basaras, D Katsaros, L Tassiulas - Big data research, 2018 - Elsevier
Abstract The advent of Solid State Drives (SSDs) stimulated a lot of research to investigate
and exploit to the extent possible the potentials of the new drive. The focus of this work is on …

A recursive algorithm for calculating the longest flow path and its iterative implementation

H Cho - Environmental Modelling & Software, 2020 - Elsevier
The longest flow path is widely used for studying hydrology. Traditionally, both or either of
upstream and downstream flow length rasters are required to calculate the longest flow path …

Reporter Ion Data Analysis Reduction (RIDAR) for isobaric proteomics quantification studies

C Jenkins, AL Norris, M O'Neill, S Das, T Andresson… - bioRxiv, 2018 - biorxiv.org
Isobaric labeling-based relative quantification techniques such as iTRAQ and TMT were
introduced 15 years ago and are now nearly ubiquitous in shotgun proteomics labs around …

Total recall: holistic metrics for broad systems performance and user experience visibility in a data-intensive computing environment

E Birngruber, P Forai, A Zauner - … Workshop on HPC User Support Tools, 2015 - dl.acm.org
User support personnel, systems engineers, and administrators of HPC installations need to
be aware of log and telemetry information from different systems in order to perform routine …

Parallel and External-Memory Algorithms for Large-Scale Genomic Sequence-Graph and-Index Construction

J Khan - 2024 - search.proquest.com
Rapid developments in the throughput and affordability of modern genome-sequencing
technologies have made the generation of billions of sequencing reads from biological …

Rapid Viral Pathogen Detection and Characterisation Using Oxford Nanopore Sequencing

E de Vries - 2023 - opal.latrobe.edu.au
Untitled Page 1 Page 2 ii OFFICIAL OFFICIAL Table of Contents Table of Contents .............................................................................................................................
ii List of Figures and Tables ............................................................................................................... iv …