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Accelerating metabolite identification in natural product research: toward an ideal combination of liquid chromatography–high-resolution tandem mass spectrometry …
Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …
organisms and assess their biological properties from either a chemical ecology or drug …
Current approaches and challenges for the metabolite profiling of complex natural extracts
Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …
research. Obtaining precise information on the chemical composition of complex natural …
Enhancing chemical and biological diversity by co-cultivation
In natural product research, microbial metabolites have tremendous potential to provide new
therapeutic agents since extremely diverse chemical structures can be found in the nearly …
therapeutic agents since extremely diverse chemical structures can be found in the nearly …
Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters
Microorganisms form diverse multispecies communities in various ecosystems. The high
abundance of fungal and bacterial species in these consortia results in specific …
abundance of fungal and bacterial species in these consortia results in specific …
Co-culturing microbial consortia: approaches for applications in biomanufacturing and bioprocessing
The application of microbial co-cultures is now recognized in the fields of biotechnology,
ecology, and medicine. Understanding the biological interactions that govern the …
ecology, and medicine. Understanding the biological interactions that govern the …
Bioprospecting endophytic fungi from Fusarium genus as sources of bioactive metabolites
RMK Toghueo - Mycology, 2020 - Taylor & Francis
Endophytic fungi became an attractive source for the discovery of new leads, because of the
complexity and the structural diversity of their secondary metabolites. The genus Fusarium …
complexity and the structural diversity of their secondary metabolites. The genus Fusarium …
Expanding the chemical diversity through microorganisms co-culture: Current status and outlook
Natural products (NPs) are considered as a cornerstone for the generation of bioactive leads
in drug discovery programs. However, one of the major limitations of NP drug discovery …
in drug discovery programs. However, one of the major limitations of NP drug discovery …
Strategies to enhance production of metabolites in microbial co-culture systems
L Guo, B **, L Lu - Bioresource Technology, 2024 - Elsevier
Increasing evidence shows that microbial synthesis plays an important role in producing
high value-added products. However, microbial monoculture generally hampers metabolites …
high value-added products. However, microbial monoculture generally hampers metabolites …
Aspergillus co-cultures: A recent insight into their secondary metabolites and microbial interactions
There is an urgent need for novel antibiotics to combat emerging resistant microbial strains.
One of the most pressing resources is Aspergillus microbial cocultures. The genome of …
One of the most pressing resources is Aspergillus microbial cocultures. The genome of …
Plant endophytes and epiphytes: burgeoning sources of known and “unknown” cytotoxic and antibiotic agents?
In the last 20 or so years, the influence of endophytes and, quite recently, epiphytes of plants
upon the compounds found in those plants, which were usually assumed to be …
upon the compounds found in those plants, which were usually assumed to be …