Pyrazolines are five-membered heterocycles possessing two adjacent nitrogens. They have
attracted significant attention from organic and medicinal chemists due to their potent …

Pyrazolines remain privileged heterocycles in drug discovery. 2-Pyrazoline scaffold has
been proven as a ubiquitous motif which is present in a number of pharmacologically …

Most of the anti-inflammatory drugs in clinical practice are becoming outdated owing to their
potential side and adverse effects. These are found to be highly unsafe for long term use …

Pyrazolines are a significant class of heterocyclic compounds with essential biological
activities. They are quite stable, which has inspired medicinal chemists to experiment with …

New hybrid thiazolyl–pyrazoline derivatives (4a–k) were obtained through a facile and
versatile synthetic procedure, and their inhibitory effects on the human carbonic anhydrase …

The synthesis and antitumor activity screening of novel 3-[2-(3, 5-diaryl-4, 5-dihydropyrazol-
1-yl)-4-oxo-4, 5-dihydro-1, 3-thiazol-5-ylidene]-2, 3-dihydro-1 H-indol-2-ones 1–23 and 3-(3 …

Heterocyclic hybrid frameworks represent a burgeoning domain within the realms of drug
discovery and medicinal chemistry, attracting considerable attention in recent years …

Introduction: Pyrazolines are well-known and important nitrogen-containing five-membered
ring heterocyclic compounds. Various methods have been worked out for their synthesis …

A series of novel 5-pyrazoline substituted 4-thiazolidinones have been synthesized. Target
compounds were evaluated for their anticancer activity in vitro within DTP NCI protocol …

This review provides a comprehensive survey relating to the synthesis and biological
applications of pyrazolines and related heterocycles in the last five years (2007–2011) …