Membrane proteins play a most important part in metabolism, signaling, cell motility,
transport, development, and many other biochemical and biophysical processes which …

Native mass spectrometry (nMS) is evolving into a workhorse for structural biology. The
plethora of online and offline preparation, separation, and purification methods as well as …

Electrospray ionization mass spectrometry (ESI-MS) is nowadays one of the cornerstones of
biomolecular mass spectrometry and proteomics. Advances in sample preparation and …

All processes that occur within living organisms are intimately linked to biological
macromolecules such as proteins, nucleic acids, or polysaccharides. Phospholipid …

Conspectus Membrane proteins play critical physiological roles and make up the majority of
drug targets. Due to their generally low expression levels and amphipathic nature …

Sphingolipids are structural lipid components of cell membranes, including membrane of
organelles, such as mitochondria or endoplasmic reticulum, playing a role in signal …

A single gene yields many forms of proteins via combinations of posttranscriptional/
posttranslational modifications. Proteins also fold into higher‐order structures and interact …

The plasma membrane of cells contains a diverse array of lipids that provide important
structural and biological features. Glycolipids are typically a minor component of the cell …

Lipoprotein nanodiscs are ideally suited for native mass spectrometry because they provide
a relatively monodisperse nanoscale lipid bilayer environment for delivering membrane …

With the emergence of next‐generation nucleotide sequencing and mass spectrometry‐
based proteomics and metabolomics tools, we have comprehensive and scalable methods …