[HTML][HTML] Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX

PA Ney - Biochimica et Biophysica Acta (BBA)-Molecular Cell …, 2015 - Elsevier
Mitochondrial autophagy (mitophagy) is a core cellular activity. In this review, we consider
mitophagy and related cellular processes and discuss their significance for human disease …

Targeting RNA for processing or destruction by the eukaryotic RNA exosome and its cofactors

JC Zinder, CD Lima - Genes & development, 2017 - genesdev.cshlp.org
The eukaryotic RNA exosome is an essential and conserved protein complex that can
degrade or process RNA substrates in the 3′-to-5′ direction. Since its discovery nearly …

Guidelines for the use and interpretation of assays for monitoring autophagy

DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin… - Autophagy, 2016 - escholarship.org
Many researchers, especially those new to the field, need to determine which criteria are
essential for demonstrating autophagy, either for the purposes of their own research, or in …

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

[HTML][HTML] Guidelines for the use and interpretation of assays for monitoring autophagy 1

DJ Klionsky, AK Abdel-Aziz, S Abdelfatah… - …, 2021 - pmc.ncbi.nlm.nih.gov
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Extracellular vesicles: evolving factors in stem cell biology

M Nawaz, F Fatima, KC Vallabhaneni… - Stem cells …, 2016 - Wiley Online Library
Stem cells are proposed to continuously secrete trophic factors that potentially serve as
mediators of autocrine and paracrine activities, associated with reprogramming of the tumor …

Putative cell type discovery from single-cell gene expression data

Z Miao, P Moreno, N Huang, I Papatheodorou… - Nature …, 2020 - nature.com
Abstract We present the Single-Cell Clustering Assessment Framework, a method for the
automated identification of putative cell types from single-cell RNA sequencing (scRNA-seq) …

The GATA factor revolution in hematology

KR Katsumura, EH Bresnick… - Blood, The Journal …, 2017 - ashpublications.org
The discovery of the GATA binding protein (GATA factor) transcription factor family
revolutionized hematology. Studies of GATA proteins have yielded vital contributions to our …

Regulation of GATA1 levels in erythropoiesis

L Gutiérrez, N Caballero, L Fernández‐Calleja… - IUBMB …, 2020 - Wiley Online Library
GATA1 is considered as the “master” transcription factor in erythropoiesis. It regulates at the
transcriptional level all aspects of erythroid maturation and function, as revealed by gene …

[HTML][HTML] Helicase-dependent RNA decay illuminated by a cryo-EM structure of a human nuclear RNA exosome-MTR4 complex

EM Weick, MR Puno, K Januszyk, JC Zinder… - Cell, 2018 - cell.com
The ribonucleolytic RNA exosome interacts with RNA helicases to degrade RNA. To
understand how the 3′ to 5′ Mtr4 helicase engages RNA and the nuclear exosome, we …