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Latest developments in metal complexes as anticancer agents
Every year novel biologically active compounds are designed as antitumor agents. This
review covers and highlights some of the most important findings described during 2018 …
review covers and highlights some of the most important findings described during 2018 …
Ruthenium complexes as anticancer agents: A brief history and perspectives
SY Lee, CY Kim, TG Nam - Drug design, development and therapy, 2020 - Taylor & Francis
Platinum (Pt)-based anticancer drugs such as cisplatin have been used to treat various
cancers. However, they have some limitations including poor selectivity and toxicity towards …
cancers. However, they have some limitations including poor selectivity and toxicity towards …
Synthesis of sorafenib− ruthenium complexes, investigation of biological activities and applications in drug delivery systems as an anticancer agent
Sorafenib, a multiple kinase inhibitor, is widely used as a first-line treatment for
hepatocellular carcinoma. However, there is a need for more effective alternatives when …
hepatocellular carcinoma. However, there is a need for more effective alternatives when …
Target based chemotherapeutic advancement of ruthenium complexes
Over the last few years, great emphasis has been given to develop ruthenium complexes to
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …
act as target specified chemotherapeutic agents. Indeed, there are few reviews available …
Metal Complexes in cancer treatment: Journey so far
Metal complexes in cancer therapy have attracted much interest mainly because metals
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …
exhibit unique characteristics, such as redox activity, metal‐ligand interaction, structure and …
Ruthenium (II)‐Dithiocarbazates as Anticancer Agents: Synthesis, Solution Behavior, and Mitochondria‐Targeted Apoptotic Cell Death
The reaction of the Ru (PPh3) 3Cl2 with HL1− 3− OH (− OH stands for the oxime hydroxyl
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …
group; HL1− OH= diacetylmonoxime‐S‐benzyldithiocarbazonate; HL2− OH …
[HTML][HTML] Biological properties of ruthenium (II)/(III) complexes with flavonoids as ligands
This review highlights the progress in the development of ruthenium (II)/(III) complexes with
flavone derivatives as potential therapeutic agents. We focused on natural hydroxyflavone …
flavone derivatives as potential therapeutic agents. We focused on natural hydroxyflavone …
Metal (triphenylphosphine)-Atovaquone complexes: Synthesis, antimalarial activity, and suppression of heme detoxification
L Daniel, A Karam, CHJ Franco, C Conde… - Inorganic …, 2024 - ACS Publications
To ascertain the bioinorganic chemistry of metals conjugated with quinones, the complexes
[Ag (ATV)(PPh3) 2](1),[Au (ATV)(PPh3)]· 2H2O (2), and [Cu (ATV)(PPh3) 2](3) were …
[Ag (ATV)(PPh3) 2](1),[Au (ATV)(PPh3)]· 2H2O (2), and [Cu (ATV)(PPh3) 2](3) were …
Synthesis and anticancer mechanisms of zinc (II)-8-hydroxyquinoline complexes with 1, 10-phenanthroline ancillary ligands
LQ Du, TY Zhang, XM Huang, Y Xu, MX Tan… - Dalton …, 2023 - pubs.rsc.org
Twenty new zinc (II) complexes with 8-hydroxyquinoline (H-Q1–H-Q6) in the presence of 1,
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …
10-phenanthroline derivatives (D1–D10) were synthesized and formulated as [Zn (Q1) 2 …
Fluorescent diorganotin (IV) complexes as anticancer agents: study of cytotoxicity, cellular localization, and mechanism of cell death
Three luminescent mixed ligand diorganotin (IV) complexes [Sn2Ph4 (L) 1–3 (DPA)(MeOH)
Cl](where L1=(Z)-N-((E)-3-ethoxy-2-hydroxybenzylidene) isonicotinohydrazonic acid, L2=(Z) …
Cl](where L1=(Z)-N-((E)-3-ethoxy-2-hydroxybenzylidene) isonicotinohydrazonic acid, L2=(Z) …