The impact of adult neurogenesis on affective functions: of mice and men

M Alonso, AC Petit, PM Lledo - Molecular Psychiatry, 2024 - nature.com
In most mammals, new neurons are not only produced during embryogenesis but also after
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …

Neurodevelopmental and functional outcomes following in utero exposure to antiseizure medication: a systematic review

E Honybun, E Cockle, CB Malpas, TJ O'Brien, FJ Vajda… - Neurology, 2024 - neurology.org
Background and Objectives To undertake a systematic review of the available literature to
examine the relationship between prenatal antiseizure medication (ASM) exposure and …

Brain Chimeroids reveal individual susceptibility to neurotoxic triggers

N Antón-Bolaños, I Faravelli, T Faits, S Andreadis… - Nature, 2024 - nature.com
Interindividual genetic variation affects the susceptibility to and progression of many
diseases,. However, efforts to study how individual human brains differ in normal …

Risk of major congenital malformations and exposure to antiseizure medication monotherapy

D Battino, T Tomson, E Bonizzoni, J Craig… - JAMA …, 2024 - jamanetwork.com
Importance Women with epilepsy (WWE) require treatment with antiseizure medications
(ASMs) during pregnancy, which may be associated with an increased risk of major …

Prenatal exposure to antiseizure medication and incidence of childhood-and adolescence-onset psychiatric disorders

JW Dreier, MH Bjørk, S Alvestad, M Gissler… - JAMA …, 2023 - jamanetwork.com
Importance Prenatal antiseizure medication (ASM) exposure has been associated with
adverse early neurodevelopment, but associations with a wider range of psychiatric end …

Valproate use during spermatogenesis and risk to offspring

J Christensen, BB Trabjerg, JW Dreier - JAMA network open, 2024 - jamanetwork.com
Importance Concerns exist about teratogenic and long-term neurodevelopmental outcomes
of paternal use of valproate during spermatogenesis. Objective To evaluate the association …

Comparative safety of antiseizure medication monotherapy for major malformations

JM Cohen, S Alvestad, CE Cesta, MH Bjørk… - Annals of …, 2023 - Wiley Online Library
Objective This study was undertaken to examine the comparative safety of antiseizure
medication (ASM) monotherapy in pregnancy with respect to risk of major congenital …

Health equity, care access and quality in headache–part 2

B Raffaelli, E Rubio-Beltrán, SJ Cho, R De Icco… - The journal of headache …, 2023 - Springer
Background Headache disorders are a global public health concern affecting diverse
populations. This review examines headache service organizations in low-, middle-, and …

Management of epilepsy during pregnancy and lactation

OA Hope, KMJ Harris - bmj, 2023 - bmj.com
Epilepsy is a group of neurological diseases characterized by susceptibility to recurrent
seizures. Antiseizure medications (ASMs) are the mainstay of treatment, but many …