Cancer cells face various metabolic challenges during tumor progression, including growth
in the nutrient-altered and oxygen-deficient microenvironment of the primary site …

Highlights The ultrasmall gold nanoparticles (AuNPs), serving as a bridge between small
molecules and traditional inorganic nanoparticles, create significant opportunities to address …

Simple Summary The CREB-binding protein (CBP) and p300 are paralogous lysine
acetyltransferases that serve as critical co-activators for transcription factors involved in …

Microbial rhodopsin (MRs) ion channels and pumps have become invaluable optogenetic
tools for neuroscience as well as biomedical applications. Recently, MR-optogenetics …

Perfluorooctanoic acid (PFOA) alternatives such as hexafluoropropylene oxide homologs
(HFPOs) cause concern due to increased occurrence in the environment as well as potential …

Increased metabolic activity usually provides energy and nutrients for biomass synthesis
and is indispensable for the progression of the cell cycle. Here, we find a role for α …

Brain pH has been proven to be a key factor in maintaining normal brain function. The
relationship between local pH fluctuation and brain disease has not been extensively …

Detection of slight pH changes in skin interstitial fluid (ISF) is crucial yet challenging for
studying pathological processes and understanding personal health conditions. In this work …

Perfluorobutanoic acid (PFBA) is an emerging contaminant that was demonstrated to exhibit
estrogen effects via action on classic estrogen receptors (ERs) in a low-activity manner. The …

Intracellular pH variations are a crucial indicator of physiological and pathological
conditions. As such, cancer is known to have a direct interplay with pH dysregulation. For …