Exercise intolerance (EI) is the primary manifestation of chronic heart failure with preserved
ejection fraction (HFpEF), the most common form of heart failure among older individuals …

Heart failure with preserved ejection fraction (HFpEF) is one of the most common forms of
heart failure; its prevalence is increasing, and outcomes are worsening. Affected patients …

Patients with heart failure with preserved ejection fraction (HFpEF) universally complain of
exercise intolerance and dyspnoea as key clinical correlates. Cardiac as well as …

Introduction: Coronavirus disease 2019 (COVID-19) is a systemic disease characterized by
a disproportionate inflammatory response in the acute phase. This study sought to identify …

BACKGROUND: We identified peripherally limited patients using cardiopulmonary exercise
testing and measured skeletal muscle oxygen transport and utilization during invasive single …

BACKGROUND: Obesity and adiposity are associated with an increased risk of heart failure
with preserved ejection fraction (HFpEF); yet, specific underlying mechanisms remain …

Background The renal sympathetic nervous system modulates systemic blood pressure,
cardiac performance, and renal function. Pathological increases in renal sympathetic nerve …

Abstract Background and Purpose Sodium glucose cotransporter 2 inhibitors (SGLT2i) have
emerged as a potent therapy for heart failure with preserved ejection fraction (HFpEF) …

Understanding the link between heart disease and frailty in older adults is crucial. Although
medical progress has extended life, it has not fully addressed the decline in function and …

BACKGROUND: Heart failure with preserved ejection fraction is associated with significant
functional limitations, yet treatments for improving exercise performance have been elusive …