Nucleic acid aptamers are oligonucleotide chains with molecular recognition properties.
Compared with antibodies, aptamers show advantages given that they are readily produced …

Infectious diseases present significant challenges to global health, thereby extensively
affecting both human society and the economy. In recent years, functional probes have …

Conventional nucleic acid detection technologies usually rely on amplification to improve
sensitivity, which has drawbacks, such as amplification bias, complicated operation, high …

Our previously discovered monomeric aptamer for SARS-CoV-2 (MSA52) possesses a
universal affinity for COVID-19 spike protein variants but is ultimately limited by its ability to …

Surface proteins of cells are generally recognized through receptor–ligand interactions
(RLIs) in disease diagnosis, but their nonuniform spatial distribution and higher-order …

DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …

Coronavirus transmission and mutations have brought intensive challenges on pandemic
control and disease treatment. Develo** robust and versatile antiviral drugs for viral …

Mosaic nanoparticle vaccines with heterotypic antigens exhibit broad‐spectrum antiviral
capabilities, but the impact of antigen proportions and distribution patterns on vaccine …

Engineering photo-plasmonic platforms with heterometallic nanohybrids are of paramount
significance for realizing augmented sensitivity in fluorescence-based analytical detection …

A major impediment to the clinical translation of DNA tiling nanostructures is a technical
bottleneck for the programmable assembly of DNA architectures with well-defined local …