The state of complement in COVID-19

B Afzali, M Noris, BN Lambrecht… - Nature Reviews …, 2022 - nature.com
Hyperactivation of the complement and coagulation systems is recognized as part of the
clinical syndrome of COVID-19. Here we review systemic complement activation and local …

[HTML][HTML] The case of complement activation in COVID-19 multiorgan impact

M Noris, A Benigni, G Remuzzi - Kidney international, 2020 - Elsevier
The novel coronavirus disease COVID-19 originates in the lungs, but it may extend to other
organs, causing, in severe cases, multiorgan damage, including cardiac injury and acute …

SARS-CoV-2 and coagulation disorders in different organs

S Vinayagam, K Sattu - Life sciences, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a prominent pandemic disease that
emerged in China and hurriedly stretched worldwide. There are many reports on COVID-19 …

Staphylococcus aureus modulation of innate immune responses through Toll-like (TLR), (NOD)-like (NLR) and C-type lectin (CLR) receptors

F Askarian, T Wagner, M Johannessen… - FEMS microbiology …, 2018 - academic.oup.com
Early recognition of pathogens by the innate immune system is crucial for bacterial
clearance. Many pattern recognition receptors (PRRs) such as Toll-like (TLRs) and (NOD) …

Mesenchymal stromal cell treatment prevents H9N2 avian influenza virus-induced acute lung injury in mice

Y Li, J Xu, W Shi, C Chen, Y Shao, L Zhu, W Lu… - Stem cell research & …, 2016 - Springer
Background The avian influenza virus (AIV) can cross species barriers and expand its host
range from birds to mammals, even humans. Avian influenza is characterized by …

Status of mannose-binding lectin (MBL) and complement system in COVID-19 patients and therapeutic applications of antiviral plant MBLs

A Gupta, GS Gupta - Molecular and Cellular Biochemistry, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease caused by a virus
called “Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).” In the majority of …

Glycomic analysis of host response reveals high mannose as a key mediator of influenza severity

DW Heindel, S Koppolu, Y Zhang, B Kasper… - Proceedings of the …, 2020 - pnas.org
Influenza virus infections cause a wide variety of outcomes, from mild disease to 3 to 5
million cases of severe illness and∼ 290,000 to 645,000 deaths annually worldwide. The …

New treatments for influenza

S Barik - BMC medicine, 2012 - Springer
Influenza has a long history of causing morbidity and mortality in the human population
through routine seasonal spread and global pandemics. The high mutation rate of the RNA …

Inhibition of complement activation alleviates acute lung injury induced by highly pathogenic avian influenza H5N1 virus infection

S Sun, G Zhao, C Liu, X Wu, Y Guo, H Yu… - American journal of …, 2013 - atsjournals.org
The acute lung injury (ALI) that occurs after the highly pathogenic avian influenza H5N1
virus infection is associated with an abnormal host innate immune response. Because the …

Influenza virus N-linked glycosylation and innate immunity

IA York, J Stevens, IV Alymova - Bioscience reports, 2019 - portlandpress.com
Influenza viruses cause seasonal epidemics and sporadic pandemics in humans. The
virus's ability to change its antigenic nature through mutation and recombination, and the …