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Synergistic investigation of natural and synthetic C1-trophic microorganisms to foster a circular carbon economy
A true circular carbon economy must upgrade waste greenhouse gases. C1-based
biomanufacturing is an attractive solution, in which one carbon (C1) molecules (eg CO2 …
biomanufacturing is an attractive solution, in which one carbon (C1) molecules (eg CO2 …
Metabolomics and microbial metabolism: toward a systematic understanding
Over the past decades, our understanding of microbial metabolism has increased
dramatically. Metabolomics, a family of techniques that are used to measure the quantities of …
dramatically. Metabolomics, a family of techniques that are used to measure the quantities of …
Metabolomics-based development of bioproduction processes toward industrial-scale production
Highlights•Metabolomics accelerates bioproduction via strain, culture, and model
improvement.•Metabolomics is a powerful driving force for the DBTL-based strain …
improvement.•Metabolomics is a powerful driving force for the DBTL-based strain …
Understanding the stringent response: experimental context matters
J Dworkin - Mbio, 2023 - journals.asm.org
As rapidly growing bacteria begin to exhaust essential nutrients, they enter a state of
reduced growth, ultimately leading to stasis or quiescence. Investigation of the response to …
reduced growth, ultimately leading to stasis or quiescence. Investigation of the response to …
Optimized Fast Filtration-Based Sampling and Extraction Enables Precise and Absolute Quantification of the Escherichia coli Central Carbon Metabolome
LB Thorfinnsdottir, L García-Calvo, GH Bø, P Bruheim… - Metabolites, 2023 - mdpi.com
Precise and accurate quantification is a prerequisite for interpretation of targeted
metabolomics data, but this task is challenged by the inherent instability of the analytes. The …
metabolomics data, but this task is challenged by the inherent instability of the analytes. The …
Coenzyme biosynthesis in response to precursor availability reveals incorporation of β-alanine from pantothenate in prototrophic bacteria
Coenzymes are important for all classes of enzymatic reactions and essential for cellular
metabolism. Most coenzymes are synthesized from dedicated precursors, also referred to as …
metabolism. Most coenzymes are synthesized from dedicated precursors, also referred to as …
Optogenetic manipulation of cellular energetics in Escherichia coli
T Schmidlechner - 2024 - era.ed.ac.uk
Optogenetics is a powerful research tool due to the unrivalled spatiotemporal precision and
non-invasiveness of light. Proteorhodopsin from SAR86 γ-proteobacterium (PR), a light …
non-invasiveness of light. Proteorhodopsin from SAR86 γ-proteobacterium (PR), a light …