Kidney transplantation remains the gold standard treatment for patients suffering from end-
stage kidney disease. To meet the constantly growing organ demands grafts donated after …

The high demand for organs in kidney transplantation and the expansion of the donor pool
have led to the widespread implementation of machine perfusion technologies. In this study …

Hypothermic Oxygenated Perfusion (HOPE) of the liver can reduce the incidence of early
allograft dysfunction (EAD) and failure in extended criteria donors (ECD) grafts, although …

Long-time ischemia worsening transplant outcomes in vascularized composite
allotransplantation (VCA) is often neglected. Ischemia-reperfusion injury (IRI) is an …

Hypothermic machine perfusion (HMP) has become the new gold standard in clinical donor
kidney preservation and a promising novel strategy in higher risk donor livers in several …

Background Machine perfusion is an organ preservation strategy used to improve function
over simple storage in a cold environment. This article presents an updated systematic …

Delayed graft function (DGF) is a common complication after kidney transplant. Despite
extensive literature on the topic, the extant definition of DGF has not been conducive to …

The limited supply and rising demand for kidney transplantation has led to the use of
allografts more susceptible to ischemic reperfusion injury (IRI) and oxidative stress to …

Organ transplantation remains the treatment of last resort in case of failure of a vital organ
(lung, liver, heart, intestine) or non-vital organ (essentially the kidney and pancreas) for …

The use of high-risk renal grafts for transplantation requires the optimization of pretransplant
assessment and preservation reconditioning strategies to decrease the organ discard rate …